Can a simple inhaler shield lung cancer patients from radiation side effects?

NCT ID NCT03803787

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether taking inhaled budesonide (a steroid) twice daily during radiation therapy can reduce the severity of radiation pneumonitis—a common and serious lung inflammation—in people with non-small cell lung cancer. About 72 patients will be randomly assigned to receive the inhaler or not. The goal is to see if the steroid lowers the grade of pneumonitis and whether it affects the cancer treatment's success.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Inhaled budesonide (a steroid)

What this could lead to

If it works, this could offer a simple way to prevent or lessen lung inflammation caused by radiation therapy in lung cancer patients.

What could go wrong

This is a small, early-phase trial with only 72 participants, so results may not apply broadly. The steroid may not reduce pneumonitis or could affect the cancer treatment's effectiveness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

lung disorder Lung Injury non-small cell lung carcinoma Radiation Fibrosis Syndrome respiratory tract neoplasm Thoracic Neoplasms radiation pneumonitis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Instituto Nacional de Cancerologia

    RECRUITING

    Mexico City, 14080, Mexico

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Instituto Nacional de Enfermedades Respiratorias

    ACTIVE_NOT_RECRUITING

    Mexico City, 14080, Mexico