Tiny study aims to unlock secrets of radiation lung damage

NCT ID NCT06557343

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at lung inflammation caused by radiation therapy for cancer, called radiation pneumonitis. Researchers will take cell samples from the lungs of 5 patients during a routine bronchoscopy and use a technique called single-cell sequencing to see which cells are active. The goal is to better understand what drives this serious side effect, which could help develop future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could identify specific cell signals involved in radiation pneumonitis, pointing toward new drug targets or a larger trial to develop treatments.

What could go wrong

This is a very small, early feasibility study with only 5 participants. It is not testing a treatment, so it may not lead directly to any therapy. The technique may not work as hoped.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neoplasm radiation pneumonitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre for Information Research, University of Edinburgh

    NOT_YET_RECRUITING

    Edinburgh, EH16 4UU, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Edinburgh Cancer Centre

    RECRUITING

    Edinburgh, EH4 2XU, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Henderson Lab

    NOT_YET_RECRUITING

    Edinburgh, EH16 4UU, United Kingdom

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••