Tiny study aims to unlock secrets of radiation lung damage
NCT ID NCT06557343
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at lung inflammation caused by radiation therapy for cancer, called radiation pneumonitis. Researchers will take cell samples from the lungs of 5 patients during a routine bronchoscopy and use a technique called single-cell sequencing to see which cells are active. The goal is to better understand what drives this serious side effect, which could help develop future treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could identify specific cell signals involved in radiation pneumonitis, pointing toward new drug targets or a larger trial to develop treatments.
- What could go wrong
- This is a very small, early feasibility study with only 5 participants. It is not testing a treatment, so it may not lead directly to any therapy. The technique may not work as hoped.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centre for Information Research, University of Edinburgh
NOT_YET_RECRUITINGEdinburgh, EH16 4UU, United Kingdom
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Edinburgh Cancer Centre
RECRUITINGEdinburgh, EH4 2XU, United Kingdom
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Henderson Lab
NOT_YET_RECRUITINGEdinburgh, EH16 4UU, United Kingdom
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