Gut bacteria may hold key to stronger muscles in aging

NCT ID NCT07749118

Recruiting now Disease control Sponsor: Pusan National University Yangsan Hospital Source: ClinicalTrials.gov ↗

First seen Aug 06, 2026 · Last updated Aug 11, 2026 · Updated 3 times

Summary

This trial tests whether a daily capsule containing pasteurized Akkermansia muciniphila HB05, a type of gut bacteria, can improve muscle strength in adults aged 50 to 80 with sarcopenia or possible sarcopenia. Participants take the supplement or a placebo for 24 weeks while doing regular walking and resistance exercise. The study measures changes in leg muscle strength, muscle mass, and physical performance to see if the probiotic offers a benefit.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: pasteurized Akkermansia muciniphila HB05 (a probiotic supplement)
What this could lead to: If it works, this could point toward a simple daily supplement to help older adults maintain muscle strength and independence.
What could go wrong: This is a small early-stage trial, so results may not apply broadly. The supplement may not improve muscle strength, and its long-term safety is not yet established.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSSIBLE SARCOPENIA SARCOPENIA

Contacts and locations

Locations

Pusan National University Yangsan Hospital
RECRUITING

Yangsan, 50612, South Korea

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