AI reads CT scans to measure muscle and fat: will it beat the experts?

NCT ID NCT07600866

Not yet recruiting Diagnosis Sponsor: Nucleo Research, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a new AI software called Soma that automatically measures muscle and fat from CT scans. Researchers will compare the software's measurements to those made by three expert radiologists using 200 CT scans from public databases. The goal is to see if the AI is accurate enough to help diagnose conditions like muscle loss (sarcopenia) and obesity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Soma Body-Composition Segmentation Software (diagnostic test)
What this could lead to: If successful, this software could help doctors quickly and accurately measure muscle and fat from CT scans, aiding in the diagnosis of conditions like sarcopenia and obesity.
What could go wrong: This is a small, early validation study using existing scans, not a real-world test. The software may not perform as well in different hospitals or on different types of patients.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BODY COMPOSITION OBESITY SARCOPENIA

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Nucleo Research, Inc.

San Francisco, California, 94133, United States

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