QUALITY OF LIFE (QOL)

This study tests whether an extra injection of a long-lasting anesthetic (bupivacaine with epinephrine) after a root canal can lower pain, improve daily comfort, and reduce the need for painkillers. About 150 adults with tooth pain will be randomly assigned to receive the anesthe…

This study tests whether a therapy called Mindful Self-Compassion (MSC) can help people with borderline personality disorder (BPD) feel better. Researchers will enroll 60 adults with BPD to see if MSC reduces self-harm, improves emotional control, and boosts quality of life. The …

This study looks at how to improve quality of life for people with a Left Ventricular Assist Device (LVAD) and their family caregivers. Participants complete two surveys—one in the hospital and one two months after discharge—and may receive mental health resources. The goal is to…

This study tests whether combining electroacupuncture (a gentle electric current through thin needles) with self-acupressure (pressing specific points on the body) can improve quality of life for people with early-stage breast cancer who are undergoing chemotherapy. About 192 par…

This study tests whether an intensive follow-up program can improve bowel control and quality of life for people who have had rectal cancer surgery. About 140 adults who have bowel problems after surgery will either get the intensive program or standard care. The program includes…

This study tests whether starting a structured exercise and education program soon after a hospital stay for a pulmonary embolism (a blood clot in the lungs) can improve quality of life and reduce long-term symptoms like shortness of breath. About 160 high-risk adults will be ran…

This study tests whether remote nutritional counseling helps cancer patients stick to their treatment and feel better. 240 adults with invasive cancer who are about to start therapy will receive either a one-time consultation with written materials or a more intensive program wit…

This study tests a 10-week online group program for adults with spina bifida to improve self-esteem, quality of life, and reduce anxiety and depression. Participants attend weekly 1.5-hour video sessions with 6-7 others, plus two follow-ups. The goal is to strengthen social skill…

This study looks at whether a pre-surgery program of exercise and a special nutritional drink (Ocoxin®) can help women with gynecologic cancers recover better after surgery. About 100 participants will follow this program alongside standard ERAS recovery steps. The goal is to see…

This study tests whether a computer model (machine learning) can help prevent vomiting in children being treated for cancer. About 1,332 children admitted to the hospital will have their risk of vomiting in the next 96 hours predicted daily. Pharmacists will then alert the medica…

This study tests whether adding acupuncture to herbal treatment can improve ADHD symptoms in children aged 6 to 12. Researchers will measure attention, behavior, and quality of life using parent questionnaires and interviews. The goal is to see if acupuncture offers extra benefit…

This study observes rehabilitation practices in intensive care units (ICUs) around the world for patients who need a breathing machine (mechanical ventilation) for at least 48 hours. Researchers want to understand what types of rehab are used, how often, and how they affect patie…

This study aims to understand the quality of life, medical care satisfaction, and unmet needs of people who have lived with sarcoma for 5 years or more. Researchers will survey 1,600 survivors and interview up to 60 participants in Germany. The goal is to learn what challenges su…

This study looks at children under 18 who have a tracheostomy (a tube in the windpipe to help breathing). Researchers want to find out how common feeding difficulties are in these children and whether those difficulties are linked to lower quality of life. The study will intervie…

This study looks at how caring for a child with type 1 diabetes affects parents' work, daily life, and well-being. Researchers will survey 100 Canadian caregivers to measure lost productivity, healthcare use, and quality of life. The goal is to better understand the real-world bu…

This study follows 3000 women with early-stage breast cancer to understand how treatments like surgery, chemo, and radiation affect their quality of life and cause side effects. Participants will fill out surveys and have heart, lung, and blood tests over time. The goal is to lea…