Exercise after a blood clot in the lungs: a new hope for recovery?

NCT ID NCT07143539

Recruiting now Symptom relief Sponsor: Insel Gruppe AG, University Hospital Bern Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether starting a structured exercise and education program within a month of a pulmonary embolism (a blood clot in the lungs) can prevent long-term problems like poor quality of life, shortness of breath, and reduced physical ability. About 160 hospitalized patients at higher risk for these issues will be randomly assigned to either the rehab program or standard care. Researchers will track changes in quality of life, exercise capacity, and symptoms over 180 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: exercise-based rehabilitation program
What this could lead to: If it works, this could show that structured exercise soon after a pulmonary embolism helps patients feel better, breathe easier, and return to normal activities faster.
What could go wrong: This is a relatively small, early-stage trial (160 participants) testing a non-drug intervention. Results may not apply to all patients, and the benefits might be modest or not statistically significant.

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Conditions

The condition(s) this trial relates to.

anxiety disorder Depression disease Dyspnea human disease mixed anxiety and depressive disorder pulmonary embolism venous thromboembolism Venous Thrombosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANXIETY DEPRESSION DYSPNEA EXERCISE THERAPY EXERCISE TOLERANCE FUNCTIONAL STATUS HUMANS PULMONARY EMBOLISM (DIAGNOSIS) QUALITY OF LIFE (QOL) REHABILITATION EXERCISE VENOUS THROMBOEMBOLISM (VTE)

Contacts and locations

Locations

Cantonal Hospital Aarau
RECRUITING

Aarau, Switzerland
Cantonal Hospital Baden
RECRUITING

Baden, Switzerland
Geneva University Hospitals
RECRUITING

Geneva, Switzerland
Inselspital, Bern University Hospital
RECRUITING

Bern, 3010, Switzerland
Lausanne University Hospital
RECRUITING

Lausanne, Switzerland
University Hospital Zürich
RECRUITING

Zurich, Switzerland

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