ANXIETY DEPRESSION

This study tests a group therapy method called I-Reconstruction to see if it helps adults with anxiety feel better. 36 people will attend 10 weekly online sessions with breathing exercises and group discussions. Researchers will compare their progress to people receiving usual ca…

This study tests whether a telemedicine-delivered cognitive behavioral program (RxWell) can help patients use fewer opioid painkillers after knee or hip replacement. About 150 adults with mild to moderate anxiety or depression symptoms will be enrolled. The program aims to improv…

This study tests a 10-session group therapy for teens aged 15-18 with autism and anxiety or depression. It aims to see if the therapy is practical, acceptable, and helpful for reducing symptoms and improving quality of life. About 36 participants will take part in the treatment a…

This study tests whether a supplement called pregnenolone can help reduce depression in people living with HIV. Researchers will give either pregnenolone or a placebo pill to 120 adults with HIV and depression, while they continue their usual antidepressant medications. Brain sca…

This study tests whether practicing five simple daily actions can reduce symptoms of anxiety and depression. About 410 adults in Norway with mild to moderate symptoms will be randomly assigned to try these actions, a gratitude practice, or be on a waitlist. The goal is to see if …

This study tests whether starting a structured exercise and education program soon after a hospital stay for a pulmonary embolism (a blood clot in the lungs) can improve quality of life and reduce long-term symptoms like shortness of breath. About 160 high-risk adults will be ran…

This study tests whether socio-aesthetics (specialized beauty and skin care) can improve quality of life, reduce pain, and ease anxiety in adults with lung, breast, colon, or prostate cancer who are receiving chemotherapy. About 400 participants will either receive socio-aestheti…

This study tests whether combining a stepped-care counseling program with an exercise program can help Latina cancer survivors reduce stress, anxiety, and depression while increasing physical activity. About 20 participants who are currently in or recently finished cancer treatme…

This study looks at how being told you have an unruptured brain aneurysm affects your mental health, specifically anxiety and depression. Researchers will compare two groups: people who are simply monitored over time and those who receive treatment. The goal is to understand whet…

This study will analyze existing medical records from about 12,000 people treated for depression, OCD, or anxiety at Greenbrook clinics. Researchers want to compare how well two treatments—NeuroStar TMS and esketamine—reduce symptoms like low mood. No new treatments are given; th…

This study looks at whether giving parents of children with chronic conditions a mental health questionnaire during clinic visits can help identify stress, anxiety, or depression. About 100 parents will fill out the survey, get their results, and receive a list of support service…

This study will analyze data from up to 156,000 people who received NeuroStar TMS for depression, OCD, or anxiety. Researchers want to learn how patient age, symptoms, and treatment settings affect results. The goal is to improve real-world use of TMS, not to test a new treatment…