Lung cancer clue: DNA repair flaw may guide future treatments

NCT ID NCT07303218

First seen Jan 04, 2026 · Last updated Jun 12, 2026 · Updated 29 times

Summary

This study looks at a DNA repair issue called homologous recombination deficiency (HRD) in people with a certain type of advanced lung cancer (EGFR-mutated NSCLC). Researchers want to find out how common HRD is and whether it affects how the cancer behaves or responds to treatment. About 100 participants will provide tissue samples and medical data, and lab experiments will help explore if these patients might benefit from PARP inhibitor drugs in the future.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dept. Medical Oncology

    Milan, MI, 20132, Italy

Conditions

Explore the condition pages connected to this study.