Sound waves could replace biopsies for gut scarring detection
NCT ID NCT06516237
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study explores whether ultrasound and elastography can detect fibrosis (scarring) in the gut of people with ulcerative colitis. Researchers will compare ultrasound images with tissue samples from biopsies to find new biomarkers. The goal is to develop a non-invasive method to assess disease severity, potentially reducing the need for repeated colonoscopies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a non-invasive way to detect fibrosis in ulcerative colitis using ultrasound, reducing the need for biopsies.
- What could go wrong
- This is an early-stage observational study with only 50 participants. The findings may not apply to all patients or lead to immediate clinical changes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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IRCCS San Raffaele Hospital, Milano
RECRUITINGMilan, Lombardy, 20132, Italy
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