Can a glass of pomegranate juice tame gut inflammation?

NCT ID NCT03000101

First seen Jul 31, 2026 ยท Last updated Jul 31, 2026

Summary

This trial investigates whether drinking pomegranate juice for 12 weeks can reduce gut inflammation in people with Crohn's disease or ulcerative colitis who are in remission. Participants will drink either pomegranate juice or a placebo beverage twice daily, and researchers will measure changes in fecal calprotectin, a marker of intestinal inflammation, along with other inflammatory indicators. The goal is to see if this natural drink could help keep inflammation in check.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
100% pomegranate juice
What this could lead to
If effective, drinking pomegranate juice could become a simple dietary addition to help manage inflammation in people with inflammatory bowel disease.
What could go wrong
This is a small early-stage trial, so results may not apply broadly. The juice may not significantly lower inflammation, and it is not a replacement for standard medical therapy.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • U.O. Gastroenterologia - Azienda Ospedaliero-Universitaria di Bologna, Policlinico Sant'Orsola-Malpighi

    Bologna, 40138, Italy

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