Can a glass of pomegranate juice tame gut inflammation?
NCT ID NCT03000101
First seen Jul 31, 2026 ยท Last updated Jul 31, 2026
Summary
This trial investigates whether drinking pomegranate juice for 12 weeks can reduce gut inflammation in people with Crohn's disease or ulcerative colitis who are in remission. Participants will drink either pomegranate juice or a placebo beverage twice daily, and researchers will measure changes in fecal calprotectin, a marker of intestinal inflammation, along with other inflammatory indicators. The goal is to see if this natural drink could help keep inflammation in check.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- 100% pomegranate juice
- What this could lead to
- If effective, drinking pomegranate juice could become a simple dietary addition to help manage inflammation in people with inflammatory bowel disease.
- What could go wrong
- This is a small early-stage trial, so results may not apply broadly. The juice may not significantly lower inflammation, and it is not a replacement for standard medical therapy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
U.O. Gastroenterologia - Azienda Ospedaliero-Universitaria di Bologna, Policlinico Sant'Orsola-Malpighi
Bologna, 40138, Italy
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