QUALITY OF LIFE

This study compares how well pressure ulcers (bedsores) heal in older adults receiving care at home versus in a long-term care facility. It also looks at quality of life, patient satisfaction, and treatment costs. Eighty people aged 60 to 90 with stage II-IV pressure ulcers will …

This trial tests whether adding a Chinese herbal formula called Shuganhuazhuo to standard anti-cancer therapy can improve liver function and survival in people with advanced hepatocellular carcinoma (the most common type of liver cancer). The study includes 120 adults who are abo…

This trial tests a 12-week program called EmpowerHer that combines home-based exercise via a mobile app with weekly in-person group sessions. It aims to improve health-related quality of life, reduce fatigue, anxiety, and depression, and increase physical fitness in breast cancer…

This study compares a new, simpler treatment called CTZ paste against the standard root canal procedure for infected baby teeth in emergency settings. The CTZ paste is placed directly into the tooth without drilling or cleaning the root canals, aiming to kill bacteria and save th…

This study tests whether five virtual sessions with a trained pharmacist can improve blood sugar, diabetes knowledge, medication adherence, and quality of life in adults with uncontrolled type 2 diabetes. Participants are randomly assigned to receive the tele-education program pl…

This study will test whether a coordinated care model, including a care coordinator and a health mediator, can prevent sexual violence among 675 female asylum seekers in France. Participants will be randomly assigned to either this coordinated care or usual care. The main goal is…

This pilot trial tests a structured cognitive rehabilitation program called CanCOG® for cancer survivors who experience thinking difficulties—often called 'chemo brain'—after treatment for cancers outside the brain. Sixty adult survivors will be randomly assigned to either the si…

This trial tests whether Mind-Body Pilates or pressure biofeedback training better eases chronic non-specific low back pain, strengthens core muscles, and improves quality of life. Adults aged 40-55 with back pain lasting at least 12 weeks will participate in a 6-week supervised …

This study tests whether a daily 200 mg dose of cannabidiol (CBD) for 12 weeks can reduce inflammation, ease pain, improve sleep, and boost quality of life in Brazilian Jiu-Jitsu athletes. One hundred healthy athletes aged 18-40 who train at least 3 times a week will be randomly …

This study tests whether a four-week online mindfulness-based education program can help women with Polycystic Ovary Syndrome (PCOS) manage menstrual symptoms, lower stress, and improve quality of life. About 78 women with PCOS will be randomly assigned to either the program or r…

This pilot study tests whether a 12-week mindfulness program can reduce loneliness, improve sleep, and boost quality of life in Chinese adults aged 65–75 who feel lonely. Participants receive eight mindfulness lessons, texts, and phone calls, while a control group attends health …

This study tests whether using an immersive virtual reality headset during exercise can improve motivation, adherence, and emotional well-being in adults undergoing cell therapy or stem cell transplant. Participants follow a therapeutic exercise program with or without VR. The tr…

This study tests whether a training program for people caring for adults aged 65 and older at home can reduce their stress and improve their quality of life. The training covers topics like hygiene, exercise, nutrition, sleep, and medication use. Researchers will compare caregive…

This study tests whether a non-electric, hand-held temple massager—used daily for 4 weeks with a special lotion and optional lavender aromatherapy—can lower stress, improve emotional wellbeing, sleep quality, and overall quality of life in women aged 35 to 65. Participants use th…

This study tests whether nutrition coaching can improve the wellbeing, strength, and quality of life of family caregivers aged 65 and older. One hundred caregivers will receive individual and group nutrition sessions over 10 months. Researchers will compare their mental health an…

This study tests whether a 12-week home exercise program, guided by a mobile app and smartwatch, can improve exercise capacity and quality of life in people with a left ventricular assist device (LVAD). About 78 participants who recently got an LVAD and cannot attend hospital reh…

This study tests whether a robotic dog named AIBO can improve emotional well-being and quality of life in children aged 8-15 with blood cancers who are undergoing a stem cell transplant. The children will interact with AIBO while isolated in the hospital for about 30 days. Resear…

This study tests whether walking with a robot dog can improve sleep, reduce fatigue, and enhance quality of life in children aged 2-7 who are undergoing cancer treatment. Forty children will be randomly assigned to either robot-dog-assisted walks or usual care. The goal is to see…

This study tests whether a 6-week gardening and nutrition program can improve quality of life for cancer survivors. Fifteen participants will attend weekly group sessions with gardening, cooking demos, and mindfulness. The main goal is to see if the program is practical and liked…

This study tests whether watching calming virtual reality (VR) nature videos, including scenes from Saudi Arabia, can improve quality of life and emotional well-being for people receiving palliative care and their family caregivers. About 100 patient-caregiver pairs will take par…

This study tests a decision aid called BCT Aid for women newly diagnosed with breast cancer. The tool helps patients understand their surgical options and what matters most to them. Researchers will compare women who use the aid to those who get usual care, looking at decision co…

This study tests whether doing art activities (like drawing or painting) can reduce fatigue, anxiety, and improve quality of life in adults with blood cancers. Fifty-two patients will be split into two groups: one gets six art sessions over two weeks, the other gets standard care…

This study tests whether a digital platform called Beacon can help doctors better manage symptoms in people with advanced cancer. About 40 patients will wear smartwatches and answer questions about how they feel. The platform combines this data to give doctors a clearer picture o…

This study will test whether weekly gardening activities can improve the quality of life for 30 secondary school students with mild intellectual disabilities. For 8 weeks, students will spend about 40 minutes each week planting and caring for plants in a school greenhouse. Resear…

This study tests whether standing on a vibrating platform (whole body vibration) for 15 minutes, three times a week for eight weeks, can improve balance, reduce fear of falling, and enhance quality of life in people with nerve damage from chemotherapy. Thirty adults aged 30-60 wi…

This study will test whether doing Pilates exercises at home via video calls for 16 weeks can help people with multiple sclerosis (MS) walk farther and faster, improve balance, reduce fatigue and pain, and boost mood and thinking. About 50 adults with mild to moderate MS who can …

This study tests a structured psycho-social program (PSP) for adults aged 30-40 with type 2 diabetes who have mild-to-moderate mental health issues. Over 6-8 sessions, participants learn to manage stress, challenge negative thoughts, and improve daily habits. The goal is to reduc…

This study tests whether using a smartwatch and mobile app, along with standard care, can help adults with chronic low back pain manage their symptoms better. Eighty adults will be split into two groups: one gets standard treatment alone, the other also uses a smartwatch and app …

This study looks at whether craniosacral therapy, a gentle manual therapy, can reduce pain, depression, and improve body awareness and quality of life in primary caregivers of people with special needs. About 30 female caregivers aged 18-55 will either receive the therapy or be i…

This study tests whether a gentle hand-application method called Jin Shin Jyutsu can help perimenopausal women feel better emotionally and physically. Sixty women aged 40-54 will practice the technique daily for two weeks. Researchers will measure changes in quality of life, stre…

This study tests whether EMDR group therapy can help adults who experienced the April 2025 Silivri earthquake in Turkey. Forty participants will be randomly assigned to either the therapy group or a waitlist. Researchers will measure changes in PTSD, depression, anxiety, sleep qu…

This study looks at whether adding robotic-assisted walking training to regular physical therapy can improve quality of life, depression, anxiety, and fatigue in people who have had a stroke. Thirty-six adults who had a stroke at least three months ago will receive either robotic…

This study will compare a goat milk-based infant formula to a standard cow milk formula in 144 healthy babies aged 2 weeks to 3 months. Researchers will track digestive symptoms like crying, spit-up, and stool patterns using special scoring tools. The goal is to see if goat milk …

This study looks at whether a nurse-led health education program can improve quality of life, reduce depression, and help daily functioning in people who have had an ischemic stroke. About 70 participants will be split into two groups: one gets the education program, the other ge…

This study tests whether a wearable activity tracker and guided exercise app can reduce fatigue and improve quality of life in teens aged 13-18 who are undergoing cancer treatment. Half of the 50 participants will follow an 8-week structured exercise program using the wearable, w…

This study tests a structured lifestyle program for mothers who are the primary caregivers of children with autism. The program includes eight sessions over four weeks, focusing on stress management, healthy routines, and balancing daily activities. Researchers want to see if thi…

This study tests whether mindfulness-based cognitive therapy (MBCT), adapted for Vietnamese culture, can reduce depression symptoms and improve quality of life. One hundred sixty adults with mild-to-moderate depression will be recruited from eight Buddhist pagodas near Hanoi. Hal…

This study tests whether a digital mental health platform with open peer support can improve quality of life in adults with mild anxiety or depression symptoms. 82 participants will use the platform for 31 days. The goal is to see if their overall well-being, stress, and mood imp…

This study tests whether a mobile app can help women with breast cancer better manage side effects from chemotherapy, like fatigue, nausea, and sleep problems. 74 patients will either use the app plus standard care or receive standard care alone. The app includes symptom tracking…

This study compares outpatient (home) care to standard hospital care for people having their first large collapsed lung. 386 adults aged 18-50 will be randomly assigned to either go home with a small chest tube and valve or stay in the hospital. The goal is to see if home treatme…

This study looks at whether whole body vibration therapy—standing on a gently vibrating platform for 25 minutes, three times a week—can improve thinking, balance, and quality of life in older adults with mild cognitive impairment. Researchers will compare the vibration group to a…

This study tests whether a structured laughter yoga program can reduce burnout, stress, and compassion fatigue in nurse managers. Eighty nurse managers will either join laughter yoga sessions twice a week for 8 weeks or continue as usual. Researchers will measure changes in stres…

This study tests whether teaching parents of children with type 1 diabetes can improve the child's diabetes management and quality of life. About 42 families with children aged 8-12 will take part. Parents will receive special education sessions and motivational interviews. The g…

This study tracks 100 people in the UK who are getting a TAVI procedure to replace a narrowed heart valve. Researchers will measure how the procedure affects their quality of life, mental health, and thinking skills over one year. The goal is to understand the real-world benefits…

This study tests whether a health informatics platform (with educational videos and instant messaging) plus resistance band exercises can improve quality of life and reduce muscle loss in 90 people who have had surgery for esophageal cancer. Participants will either receive the 1…

This study looks back at the medical records of 60 adults with head and neck cancer who received radiation therapy, with or without chemotherapy, and used a topical mouth rinse made from olive oil, betaine, and xylitol. The goal is to see how often severe mouth sores (oral mucosi…

This study examines the most common symptoms of genitourinary syndrome of menopause (GSM) in postmenopausal women and how these symptoms impact quality of life. Researchers will also look at whether using a non-hormonal topical gel called XCM INTIM for at least 8 weeks is linked …

This study looks at whether treating gum disease (periodontitis) can improve how well people chew and their overall oral quality of life. Researchers will ask 44 adults with gum disease to fill out questionnaires, do a chewing test with colored gum, and provide saliva samples. Th…

This study looks at how obstructive sleep apnea (OSA) affects thinking skills like attention and memory, and how those changes relate to quality of life. Adults newly diagnosed with OSA will take an overnight sleep test, followed by computer tasks and questionnaires. Their result…

This study compares two ways to rebuild the nose after partial or total loss: surgery using skin flaps, or a custom-made prosthetic nose (epithesis). Researchers will ask people who had either treatment at least one year ago to fill out a questionnaire about how their nose looks …

This study translates and tests a Turkish version of the Staffordshire Questionnaire for Adolescent Idiopathic Scoliosis (SQAIS), a tool designed to measure body image and perceived deformity in teens with scoliosis. Researchers will enroll 100 adolescents aged 10–19 with idiopat…

This observational study will follow 200 women aged 45 to 60 to understand how muscle strength, bone density, body composition, physical activity, sleep, mood, and menopause symptoms relate to overall functional health. Participants will undergo simple strength tests, bone scans,…

This study follows 150 adults waiting for a kidney transplant to track how their physical and emotional health changes over time. Researchers will use a mobile app and interviews to measure frailty and quality of life. The goal is to identify patients who need extra support and i…

This study will follow 231 children aged 8–18 who had their appendix removed to see how many still have pain three months later. Researchers will also measure how pain affects their daily life and quality of life. No new treatment is being tested — the goal is simply to understan…

This study will follow 3,000 young women (ages 15-39) with cancer to understand how treatments like chemotherapy and immunotherapy impact their fertility, pregnancy outcomes, and quality of life. Researchers will also look at the safety and success of fertility preservation metho…

This study will survey 400 medical students at Sohag University in Egypt to understand how health anxiety impacts their quality of life. Participants will fill out two questionnaires: one measuring health anxiety and another assessing physical and mental well-being. The results c…

This study looks at how well people who have had a stroke can imagine movements (motor imagery) and how that relates to their neglect, arm function, daily activities, and quality of life. Researchers will assess 50 participants using tests and questionnaires. The goal is to bette…

This study will create and test a new questionnaire to measure quality of life in Chinese patients with pulmonary arterial hypertension (PAH), a serious lung condition. Researchers will work with 300 adults to ensure the tool is accurate and useful for doctors and health policy. …

This study will look at how long-acting reversible contraception (LARC) affects quality of life in women aged 18 to 45. Researchers will compare women using LARC methods to those using other birth control. They will measure changes in physical health, mental well-being, social re…

This study is testing a new questionnaire (called the QLQ-OV39) to see how well it measures quality of life in people with ovarian cancer. About 50 adults with early or advanced ovarian cancer will fill out the questionnaire and give feedback. The goal is to make sure the questio…

This study looks back at data from 80 veterans and first responders who completed a 12-week program that combined mental health support, physical therapy, nutrition advice, and occupational therapy. Researchers want to see if the program helped improve sleep, anxiety, depression,…

This pilot study will test whether a four-week lumbar stabilization exercise program can improve quality of life, motor control, and balance in healthy but sedentary adults. Forty participants will be randomly assigned to either the exercise program or a control group that receiv…

This study aims to create a nutrition algorithm called NACHO that suggests foods and recipes tailored to cancer patients' needs. Researchers will work with dietitians, clinicians, and patient advisors to develop the tool, then test it with 130 patients who are undergoing or have …

This study looks at how often women with early-stage breast cancer experience taste changes during chemotherapy. Researchers will use taste tests to measure changes in sweet, sour, salty, and bitter perception. They will also check how these changes affect nutrition and quality o…

This study looks at 38 women who had pelvic side effects (like pain in the rectum, bladder, or vagina) after radiation or chemotherapy for gynecological cancers. Researchers will compare their gut bacteria to healthy controls and see if rectal ozone therapy changes the microbiome…

This observational study follows 162 patients with blood cancers who are receiving either a stem cell transplant or CAR-T therapy. Researchers will use a questionnaire to measure how symptoms and quality of life change from the start of hospital stay to discharge. The goal is to …

This study follows 93 children aged 5-18 with brain tumors who are receiving radiation therapy. Researchers will track their nutrition and quality of life over time to see how they are connected. The goal is to create a nutrition plan and early warning system to help these childr…

This study aims to understand how chronic obstructive pulmonary disease (COPD) affects the quality of life of patients in Nepal. Researchers will ask 71 adults with COPD to complete questionnaires about their symptoms and daily activities. No treatments or medications are tested;…

This study looks at patients who needed a breathing machine for more than 48 hours in the ICU between 2021 and 2023. Researchers will interview 90 adults in 2025 to see if they still have physical, mental, or thinking problems (called post-ICU syndrome) and how it affects their q…