QUALITY OF LIFE

This trial tests whether a low-cost reusable cloth pad, along with hygiene education and support, can improve menstrual health practices among women and girls in Bangladesh. Around 700 participants in the Dhaka area will either receive the intervention or continue their usual pra…

This study looks at whether injecting special stem-like cells called Muse cells directly into the ovaries can help women aged 28 to 70 who are in perimenopause. The cells may repair tissue, reduce inflammation, and improve hormone balance. Researchers will track safety, hormone l…

This study tests a smartphone app that uses artificial intelligence to help liver transplant recipients manage their health after surgery. Researchers will track whether the app improves patients' confidence, daily self-care, and quality of life, and reduces emergency visits or i…

This study tests a new, simpler laparoscopic surgery for women with pelvic organ prolapse (when pelvic organs drop from their normal position). The goal is to restore anatomy and improve quality of life while reducing risks from surgical mesh. The study involves 60 women aged 30-…

This study looks at a new way to treat severe, long-term blockages in heart arteries (CTO). Instead of one long procedure, doctors will plan two shorter procedures. The goal is to see if this approach is safer, more successful, and better for patients. About 200 people with high-…

This trial tests whether a structured therapeutic education program, delivered by general practitioners, can improve quality of life for people with heart failure. Around 200 patients in primary care will be randomly assigned to receive the program or usual care, and their qualit…

This trial compares two yogic breathing techniques—Simha Pranayama (Lion's Breath) and Bhramari Pranayama (Humming Bee Breath)—to see if they can improve sleep and quality of life in healthy, working adults. Participants practice one of the two techniques daily for one month. Sle…

This pilot study tests whether giving dexmedetomidine and lidocaine during major non-cardiac surgery can help patients recover faster and with less pain. About 100 adults having elective surgery will be randomly assigned to receive one of these drugs or standard care. The main go…

This study tests whether a 6-week online yoga program can improve quality of life, reduce joint pain, and lessen night sweats and hot flashes in women with breast cancer who are taking endocrine therapy. About 64 women will take part, with half doing yoga four days a week and the…

This study aimed to see if a simple mindfulness breathing exercise could improve health and quality of life in people with spinal cord injury. Participants would have done a 10-15 minute guided breathing session three times a week for a month. However, the trial was withdrawn bef…

This study tests whether listening to specific sound frequencies for just 9 minutes a week can improve mental health. 110 adults with mild anxiety, stress, or depression will either sit in a special sound chamber or use headphones. The goal is to see if this simple, drug-free app…

This pilot study aimed to test whether immersive virtual reality (VR) exercises could help people with multiple sclerosis who experience dizziness, balance issues, and fatigue. Participants would have been randomly assigned to either VR-based vestibular rehab or conventional exer…

This study aimed to see if trazodone works better than quetiapine or a placebo for treating confusion (delirium) in adult surgical ICU patients. It planned to measure how long delirium lasts, sleep quality, and side effects. However, the study was withdrawn before enrolling any p…

This study tests an online self-help program called Together After Cancer for Latina breast cancer survivors and their intimate partners. The program includes brief coach calls and aims to improve the survivor's quality of life and the couple's relationship satisfaction. About 48…

This study aimed to see if a device called Sana could improve quality of life for people with fibromyalgia, a condition that causes long-term pain. Researchers planned to compare the active device to a sham (fake) device in adults aged 18 to 65 who had fibromyalgia symptoms for a…

This study tests whether watching 10-minute 360° nature videos twice a week for 12 weeks can improve quality of life, mood, and agitation in nursing home residents with dementia. Sixty residents will be randomly assigned to either the virtual nature program or their usual care. R…

This study tests whether a group-based behavioral program called Horizons can improve quality of life and coping skills in adults with chronic graft-versus-host disease (cGVHD), a common complication after stem cell transplant. The program involves 8 weekly video sessions with a …

This study aimed to see if exercise can improve physical activity and quality of life in children aged 8-18 with acute lymphoblastic leukemia who are on maintenance chemotherapy. Researchers planned to measure changes in quality of life, activity levels, sleep, and fatigue. The s…

This study tests whether a program of balance, coordination, and perception exercises can improve thinking, movement, and quality of life in 30 children with ADHD, ages 8 to 12. The training includes activities like balancing, shape perception, and eye-hand coordination. Research…

This study is testing whether a mobile app called Horizons can help adults with chronic graft-versus-host disease (a long-term complication after a bone marrow transplant) manage their symptoms and improve their quality of life. Twenty participants will use the app for about six …

This study tests whether an 8-week physical activity program can improve physical fitness and quality of life in paramedic students. Sixty students will be randomly assigned to either the exercise program or a control group. The program includes cardiovascular, strength, and flex…

This study gives 250 advanced cancer patients $1,000 each month for a year to see if it reduces financial stress and improves quality of life. Participants also complete surveys every three months. The goal is to learn whether extra income can help patients stick to treatments an…

This study tests whether MR-guided focused ultrasound (MR-HIFU), alone or with standard radiotherapy, can better relieve pain from bone metastases than radiotherapy alone. About 216 adults with painful bone lesions will be randomly assigned to one of three groups. The goal is to …

This study tests whether a 30-minute education session with a radiation therapist, before standard radiotherapy, can reduce anxiety and improve quality of life for breast cancer patients. About 109 participants will be randomly assigned to either the extra session or standard car…

This study tests a web-based decision aid called 'Roadmap to Parenthood' for young women who have completed cancer treatment and are thinking about having children. The tool provides information and planning support to help them make informed choices. Researchers will measure whe…

This study aimed to see if a food supplement called ARACOMPLEX® could help maintain quality of life in patients with advanced pancreatic cancer receiving chemotherapy. The supplement contains maca extract, vitamins, and minerals. However, the trial was withdrawn before enrolling …

This study tests whether an 8-week mobile app program, including education and counseling, can reduce urinary incontinence symptoms and improve quality of life and sleep in menopausal women. 82 women aged 40-65 are split into two groups: one uses the app with phone support, the o…

This study looks at whether teaching patients about gallstones and gallbladder removal surgery before the operation can improve their quality of life afterward. About 200 adults having gallbladder surgery will either get standard hospital care or extra educational sessions. Resea…

This study tests a new way of caring for children under 10 with diabetes. The clinic uses play, nutrition advice, mental health support, and parent groups to help families feel calmer and more in control. About 100 children and their families will take part to see if this approac…

This study tests a telehealth program called Horizons for adults who have had a stem cell transplant and developed moderate to severe chronic graft-versus-host disease (GVHD). The program uses video sessions and questionnaires to help patients cope and follow their treatment plan…

This study looks at whether giving blood transfusions to patients who are anemic after leaving the intensive care unit (ICU) can help them feel less tired and recover better. About 346 adults from UK hospitals will be randomly assigned to either the usual care (transfusions only …

This study compares two treatments for early-stage throat cancer: robotic surgery (TORS) or radiation therapy (IMRT). It looks at which one leads to better swallowing function and overall quality of life. About 138 adults with HPV-related throat cancer are taking part. The goal i…

This study tests whether a program called Bright IDEAS can help parents of children receiving palliative care feel less anxious, depressed, and stressed. The program teaches parents a step-by-step approach to solving problems. Forty parents will take part in 6-8 sessions and repo…

This study compares two types of weight-loss surgery—sleeve gastrectomy alone versus sleeve gastrectomy with transit bipartition—to see which leads to fewer cases of dumping syndrome (nausea, diarrhea, dizziness after eating) and better quality of life. Researchers will follow 20…

This study tests a 12-week program called Breathe Easier+ for people who have finished treatment for non-small cell lung cancer and their partners. The program includes guided walking, resistance training, coaching calls, and stress management delivered remotely via smartphone or…

This study tests whether a 12-week home exercise program, including aerobic and strength exercises with remote supervision, can improve quality of life and physical function in people who have had heart valve or bypass surgery. 76 participants are split into an exercise group and…

This study looks at whether weekly group drumming for 8 weeks can improve the health of people aged 60 and older living in the community. Researchers will measure changes in quality of life, depression, sleep, and blood pressure. 300 participants will take part, and the goal is t…

This study follows women with early-stage breast cancer who are about to receive paclitaxel chemotherapy, a treatment that often causes nerve damage. Researchers will use smartwatches and a mobile app to track physical activity, sleep, and stress, alongside clinical exams and ski…

This pilot study will test whether a daily 30-minute Tao Calligraphy mindfulness practice can increase mitochondrial DNA content in blood cells over 12 months. Fifty healthy or ill adults (excluding those with genetic diseases, cancer, or serious mental disorders) will provide bl…

This study explores whether attending free community events in renovated neighborhood parks can improve sleep, stress, mood, and overall well-being in adults aged 18 and older who live nearby. Participants wear a smart ring to track sleep and complete surveys over about six month…

This study tests whether offering financial coaching during pediatric checkups can improve parents' health-related quality of life and children's development. Researchers are enrolling 400 families with infants 4 months or younger at a Los Angeles safety-net clinic. Parents recei…

This study tests whether simple questionnaires can effectively measure quality of life in heart patients and job satisfaction in their caregivers. Over 1,100 participants from a French hospital will complete surveys before and after procedures like pacemaker insertion or heart su…

This study tests a digital literacy program for adults aged 65 and older to help them better communicate with their healthcare team, manage health information, and feel more socially connected. Twenty participants will learn to use digital tools in their own homes. The goal is to…

This study tests a short guide called the 'Jumpstart Guide' to help doctors have better conversations with dementia patients and their families about healthcare goals. Over 1,800 patients and their caregivers are taking part. Researchers will compare whether those whose doctors u…

This study looks at how tiredness (fatigue) affects the daily activities and quality of life of 89 children aged 2 to 18 who are being treated for cancer. Researchers will use special surveys to measure fatigue levels and see how they relate to the children's ability to do everyd…

This study follows 90 people who survived severe COVID-19 pneumonia and needed intensive care. Researchers will check their physical health, mental health, and quality of life at 3 months, 6 months, 1 year, and 5 years after leaving the ICU. The goal is to better understand the l…

This study compares open D3 surgery with laparoscopic CME surgery for right-sided colon cancer in 128 patients. The goal is to see if laparoscopic surgery leads to less pain, fewer complications, and faster recovery, while still being as effective at removing cancer. Researchers …

This study tracks 80 patients with brain tumors (metastases or meningiomas) who receive stereotactic radiosurgery. Researchers use memory tests and quality-of-life questionnaires before treatment and every 3 months for a year to see if and how brain function changes. By comparing…

This study tracks 300 adults in the Bonton neighborhood to see how taking part in farm-based wellness activities (like healthy eating and exercise programs) affects their heart health and quality of life over one year. Participants choose which activities to join, and researchers…

This observational study will follow 384 patients in Brazil who are using cannabis-based products (like CBD or THC oils) prescribed by their own doctors for chronic pain, anxiety, or depression. Researchers will not provide the medication but will track patients' quality of life,…

This study looks at how breast cancer and its treatments impact the quality of life for patients in Martinique. Researchers will survey 133 adults with invasive breast cancer to understand their physical and emotional well-being, as well as how long treatment takes. The goal is t…

This study looks at whether measuring parathyroid hormone during thyroid removal surgery can help doctors personalize care afterward. About 150 adults having their thyroid removed will be split into groups based on their hormone drop. Some will skip routine blood tests, while oth…

This study interviews 20 people aged 16-25 who have had bladder or urinary problems since childhood and are now moving from pediatric to adult care. Researchers want to learn about their experiences, challenges, and opinions to make this transition smoother for others. No treatme…

This study tests whether proactive telemedicine (phone or online check-ins) works as well as in-person visits for people in rural areas who haven't seen a doctor in over a year. Researchers will measure how many people start using healthcare again and whether their quality of lif…

This study looks at whether adding community health worker visits and free healthy groceries to the standard Meals on Wheels program can help older adults eat better, feel less lonely, and improve their quality of life. About 1,640 Rhode Island seniors at high nutritional risk wi…

This study looks at whether teaching people how to care for their mouth and teeth can improve oral health, sleep, and quality of life for those using a non-invasive ventilator at home. Thirty adults will be split into two groups: one gets standard printed leaflets, the other gets…

This study looks at how spasmodic dysphonia, a voice disorder causing uncontrollable vocal cord spasms, affects patients' jobs and social lives. Researchers will interview 20 adults who have received at least one botulinum toxin injection to understand if the treatment helps impr…

This large study will observe up to 300,000 people using a personalized digital physical activity program called Sword Move. Researchers want to see if following this program can improve overall health, quality of life, and mental health. Participants will report changes in anxie…