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Can VR help MS patients with dizziness? trial planned but withdrawn

NCT ID NCT04497025

Symptom relief Sponsor: Maria Jesus Casuso-Holgado Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled This study
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study aimed to test whether immersive virtual reality (VR) exercises could help people with multiple sclerosis who experience dizziness, balance issues, and fatigue. Participants would have been randomly assigned to either VR-based vestibular rehab or conventional exercises. However, the study was withdrawn before enrolling anyone, so no data was collected.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Immersive virtual reality-based vestibular rehabilitation
What this could lead to
If this works, it could offer a new, engaging way to help people with multiple sclerosis manage dizziness and balance problems.
What could go wrong
This trial was withdrawn before enrolling anyone, so no results exist. VR may cause cybersickness or not be more effective than standard exercises.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

Dec 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Both male and female subjects from 18-65 years old * Clinically diagnosed with any type of multiple sclerosis in accordance with the revised McDonald criteria * With walking ability according to the Expanded Disability Status Scale score (EDSS =6) * With the objective presence of dizziness symptoms (Dizziness Handicap Inventory = 16) Exclusion Criteria: * Blurred vision * Cognitive impairment (Mini Mental State Examination =24) * Another neurologic disorder contributing to balance impairment * Relapse within the last 3 months * Changes in pharmacotherapy within the last 3 months * History of vestibular rehabilitation within the last 6 months * Acute cardiovascular of respiratory illness * Any other contraindication to physical activity

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Conditions

The condition(s) this trial relates to.

Dizziness Fatigue motion sickness multiple sclerosis vestibular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Balance disorders Cybersickness Dizziness Fatigue Multiple sclerosis Quality of life Usability Vestibular disease

Contacts and locations

Locations

  • Universidad de Sevilla

    Seville, Sevilla, 41004, Spain

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