Laparoscopic vs open surgery: which is better for colon cancer recovery?

NCT ID NCT03776591

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares open D3 surgery with laparoscopic CME surgery for right-sided colon cancer in 128 patients. The goal is to see if laparoscopic surgery leads to less pain, fewer complications, and faster recovery, while still being as effective at removing cancer. Researchers will also collect blood and tumor samples to explore new ways to monitor the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could show that laparoscopic surgery improves recovery and quality of life without compromising cancer outcomes, and that liquid biopsies may better predict treatment success.
What could go wrong
This is a relatively small, single-center study comparing two surgical techniques, so results may not apply broadly. The use of liquid biopsies is exploratory and not yet proven to guide treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Haraldsplass

    Bergen, 5021, Norway

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