Olive oil and xylitol mouth rinse may shield cancer patients from painful mouth sores

NCT ID NCT07739771

First seen Jul 31, 2026 · Last updated Jul 31, 2026

Summary

This study looks back at the medical records of 60 adults with head and neck cancer who received radiation therapy, with or without chemotherapy, and used a topical mouth rinse made from olive oil, betaine, and xylitol. The goal is to see how often severe mouth sores (oral mucositis) occurred, how quickly they appeared, and how they affected quality of life, including pain, speech, and saliva. By examining past data, researchers hope to learn whether this natural rinse might help protect the mouth during cancer treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
A topical oral formulation containing olive oil, betaine, and xylitol
What this could lead to
If the data look promising, this could support a larger trial testing whether this natural mouth rinse helps prevent severe mouth sores and improve quality of life during radiation therapy.
What could go wrong
This is a small, retrospective review of past medical records, not a controlled experiment. It cannot prove the rinse works, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital Universitario HM Sanchinarro - Centro Integral Oncológico Clara Campal

    Madrid, Madrid, 28050, Spain

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