ORAL MUCOSITIS

This study tests whether a telehealth program can help cancer survivors prevent mouth sores, gum disease, and tooth decay. One hundred survivors who finished cancer treatment at least 6 months ago will either get the telehealth program or usual care. The goal is to see if the pro…

This study tests whether a one-time infusion of amimestrocel, made from donated umbilical cord cells, can prevent severe mouth and gut sores in people receiving a stem cell transplant. About 22 adults will get the infusion before their transplant, and researchers will monitor for…

This study tests whether a zinc-based spray (Gel X) can prevent painful mouth sores caused by radiation therapy for head and neck cancer. About 130 adults receiving radiation will use either the zinc spray or a sodium bicarbonate rinse. The goal is to see if the spray reduces how…

This study tests if rinsing with virgin coconut oil can prevent severe mouth sores in children and young adults (ages 7-26) getting a bone marrow transplant. About 60 participants will either use standard mouth rinses or add coconut oil to their routine. Researchers will compare …

This study tests a daily light therapy device placed inside the mouth to prevent severe mouth sores in people receiving a stem cell transplant. Twenty adults will use the device for about 2-3 minutes each day from the start of their conditioning chemotherapy through day 20 after …

This phase 2 trial is testing a topical gel and mouthwash made from olive oil, betaine, and xylitol (XCM-OM118) to see if it can reduce severe oral mucositis (painful mouth sores) in head & neck cancer patients receiving radiation. The study will enroll 63 adults and track how ma…

This study tests whether applying medical ozone gas to mouth sores can reduce pain and severity in people undergoing radiation or chemotherapy for head and neck cancer. Fifty participants will receive ozone therapy, and half will also use a special toothpaste and mouthwash at hom…

This study tests whether high-level laser therapy can help manage oral mucositis—painful mouth sores—in children under 18 who are having a bone marrow transplant. Fourteen participants will receive either laser treatment or standard mouth care (chlorhexidine and sodium bicarbonat…

This study tests if a special light treatment, called photobiomodulation, can reduce the severity and frequency of painful mouth sores in oral cancer patients receiving radiation therapy. About 30 adults who have had surgery for oral cancer will receive the light treatment five t…