ORAL MUCOSITIS

This study tests whether a telehealth program can help cancer survivors prevent mouth sores, gum disease, and tooth decay, and improve their quality of life. One hundred cancer survivors who finished treatment at least 6 months ago will either get the telehealth program or usual …

This study tests whether rinsing with virgin coconut oil can prevent severe mouth sores (oral mucositis) in children and young adults aged 7-26 who are getting high-dose chemotherapy before a bone marrow transplant. Participants will either use standard mouth rinses or add coconu…

This study tests a zinc-based spray (Gel X) to prevent oral mucositis—painful mouth sores—in 130 people receiving radiation for head and neck cancer. Participants will use either the zinc spray or a sodium bicarbonate rinse. The goal is to see if the spray reduces how many people…

This study tests whether a single infusion of amimestrocel, a cell therapy made from human umbilical cord cells, can prevent severe mouth and gut sores in patients receiving a stem cell transplant. About 22 adults will receive the infusion 1-2 days before their transplant. Resear…

This study tests a light device (photobiomodulation) to prevent severe mouth sores in 20 adults receiving a stem cell transplant. Participants get daily light treatment inside their mouth using a device called THOR LX2.3 with LED Lollipop. The goal is to see if this can reduce th…

This study tests a special gel and mouthwash (XCM-OM118) in 63 head and neck cancer patients getting radiation, with or without chemo. The goal is to see if it lowers the chance of severe mouth sores (grade 3-4) and improves quality of life. Patients use the product during radiat…

This study tests whether high-level laser therapy can help manage painful mouth sores (oral mucositis) in children undergoing bone marrow transplants. Fourteen kids with at least moderate sores will receive laser treatment on their lesions, and researchers will compare their heal…

This study tests if a special light treatment, called photobiomodulation, can reduce the severity and frequency of painful mouth sores caused by radiation therapy in oral cancer patients. About 30 adults who have had surgery for oral cancer and are scheduled for radiation will re…

This study tests if ozone gas therapy, alone or with special toothpaste and mouthwash, can reduce painful mouth sores caused by radiation or chemotherapy. About 50 adults with head and neck cancer who have mouth sores will be randomly assigned to ozone therapy or ozone plus a hom…