Could a daily 'Lollipop' light stop mouth sores in transplant patients?

NCT ID NCT05335434

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a daily light therapy device placed inside the mouth to prevent severe mouth sores in people receiving a stem cell transplant. Twenty adults will use the device for about 2-3 minutes each day from the start of their conditioning chemotherapy through day 20 after transplant. The main goal is to see how many days of severe mouth sores occur, compared to what is normally expected.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
THOR LX2.3 with LED Lollipop (a light-emitting device placed in the mouth)
What this could lead to
If it works, this could offer a simple, non-drug way to prevent painful mouth sores during stem cell transplant recovery.
What could go wrong
This is a very small pilot study with only 20 people, so results may not apply to everyone. The device may not reduce sores more than standard care.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

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