Could a laser beam stop chemo mouth sores?
NCT ID NCT01772706
First seen Jul 01, 2026 · Last updated Jul 01, 2026
Summary
This trial investigates whether a low-level diode laser can prevent or reduce severe mouth sores (mucositis) caused by radiation and chemotherapy in people with advanced head and neck cancer. Participants receive either real laser therapy or a non-functional placebo laser during their cancer treatment. The study measures how many patients develop painful mouth sores that affect eating, aiming to find a simple way to ease a common side effect.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
low-level diode laser therapy
What this could lead to
If effective, this laser treatment could become a standard way to prevent painful mouth sores during cancer therapy, improving patients' quality of life.
What could go wrong
This is a mid-stage trial with 97 participants, so results may not apply to all patients. The laser may not reduce severe mucositis more than a placebo.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Centre Guillaume le Conquérant
Le Havre, 76600, France
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Centre Jean Godinot
Reims, 51100, France
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Centre hospitalier universitaire La Milétrie
Poitiers, 86021, France
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Clinique Armoricaine de Radiologie
Saint-Brieuc, 22015, France
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Hôpital La Pitié Salpêtrière
Paris, 75013, France
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Institut de Cancerologie de l'Ouest Paul Papin
Angers, 49933, France