Could a laser beam stop chemo mouth sores?
NCT ID NCT01772706
First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time
Summary
This trial investigates whether a low-level diode laser can prevent or reduce severe mouth sores (mucositis) caused by radiation and chemotherapy in people with advanced head and neck cancer. Participants receive either real laser therapy or a non-functional placebo laser during their cancer treatment. The study measures how many patients develop painful mouth sores that affect eating, aiming to find a simple way to ease a common side effect.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- low-level diode laser therapy
- What this could lead to
- If effective, this laser treatment could become a standard way to prevent painful mouth sores during cancer therapy, improving patients' quality of life.
- What could go wrong
- This is a mid-stage trial with 97 participants, so results may not apply to all patients. The laser may not reduce severe mucositis more than a placebo.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Centre Guillaume le Conquérant
Le Havre, 76600, France
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Centre Jean Godinot
Reims, 51100, France
-
Centre hospitalier universitaire La Milétrie
Poitiers, 86021, France
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Clinique Armoricaine de Radiologie
Saint-Brieuc, 22015, France
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Hôpital La Pitié Salpêtrière
Paris, 75013, France
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Institut de Cancerologie de l'Ouest Paul Papin
Angers, 49933, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Blood test may spare throat cancer patients from full radiation
- Olive oil and xylitol mouth rinse may shield cancer patients from painful mouth sores
- Can laser or ozone therapy better soothe cancer-related mouth pain? a head-to-head comparison
- Plant pigment could soothe Radiation's harsh side effect in blood cancer treatment
- New drug aims to spare cancer patients from debilitating mouth sores
- New lozenge aims to ease radiation mouth sores for hours