Could ozone gas soothe cancer Patients' painful mouth sores?

NCT ID NCT07491536

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether applying medical ozone gas to mouth sores can reduce pain and severity in people undergoing radiation or chemotherapy for head and neck cancer. Fifty participants will receive ozone therapy, and half will also use a special toothpaste and mouthwash at home. The goal is to see if these treatments help people eat, drink, and continue cancer therapy with less discomfort.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

gas ozone therapy

What this could lead to

If it works, this could offer a simple, non-drug way to reduce mouth sore pain and help people continue cancer treatment without delays.

What could go wrong

This is a small, early-stage trial with only 50 people. Ozone therapy is not yet proven for this use, and results may not apply to everyone. Side effects are possible but not well-studied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chemotherapy-induced oral mucositis head and neck neoplasm Head and Neck Neoplasms stomatitis Xerostomia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Unit of Orthodontics and Pediatric Dentistry - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Pediatrics - University of Pavia

    RECRUITING

    Pavia, Lombardy, 27100, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••