Touch and tingle: Non-Drug therapies aim to tame chemo side effects

NCT ID NCT07711626

First seen Jul 17, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This study tests whether foot reflexology or a mild electrical nerve stimulation on the ear can reduce pain, dry mouth, fatigue, and sleep problems in people with head and neck cancer who are receiving chemoradiotherapy. Participants are randomly assigned to receive the real treatment, a sham version, or usual care, and are followed for four weeks. The goal is to find safe, drug-free ways to improve quality of life during cancer treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
foot reflexology and transcutaneous auricular vagus nerve stimulation
What this could lead to
If effective, these non-drug therapies could offer a safe, low-cost way to manage multiple debilitating side effects of chemoradiotherapy in head and neck cancer patients.
What could go wrong
This is a small, early-stage trial with sham controls, so results may not be conclusive. The benefits, if any, might be modest or not apply to all patients.

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Conditions

The condition(s) this trial relates to.

head and neck cancer head and neck neoplasm Head and Neck Neoplasms insomnia Pain Xerostomia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hualien Tzu Chi Hospital, Department of Otorhinolaryngology

    RECRUITING

    Hualien City, 970, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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