Umbilical cord cell infusion aims to prevent painful mouth sores in transplant patients
NCT ID NCT07400328
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a one-time infusion of amimestrocel, made from donated umbilical cord cells, can prevent severe mouth and gut sores in people receiving a stem cell transplant. About 22 adults will get the infusion before their transplant, and researchers will monitor for sores, pain, and side effects for up to 100 days. The goal is to see if this cell therapy reduces the rate of severe oral mucositis, a common and painful complication of transplant conditioning.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- amimestrocel (umbilical cord mesenchymal stem cells)
- What this could lead to
- If it works, this could offer a way to prevent painful mouth and gut sores in patients undergoing stem cell transplants, reducing pain and infection risk.
- What could go wrong
- This is a small, early-phase study with only 22 participants, so results may not apply to everyone. The treatment may not reduce severe mouth sores, and there could be unknown side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
First Affiliated Hospital of Soochow University
RECRUITINGSuzhu, Jiangsu, 215006, China
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Other studies related to the condition(s) this trial covers.
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