Umbilical cord cell infusion aims to prevent painful mouth sores in transplant patients
NCT ID NCT07400328
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a one-time infusion of amimestrocel, made from donated umbilical cord cells, can prevent severe mouth and gut sores in people receiving a stem cell transplant. About 22 adults will get the infusion before their transplant, and researchers will monitor for sores, pain, and side effects for up to 100 days. The goal is to see if this cell therapy reduces the rate of severe oral mucositis, a common and painful complication of transplant conditioning.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
amimestrocel (umbilical cord mesenchymal stem cells)
What this could lead to
If it works, this could offer a way to prevent painful mouth and gut sores in patients undergoing stem cell transplants, reducing pain and infection risk.
What could go wrong
This is a small, early-phase study with only 22 participants, so results may not apply to everyone. The treatment may not reduce severe mouth sores, and there could be unknown side effects.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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First Affiliated Hospital of Soochow University
RECRUITINGSuzhu, Jiangsu, 215006, China
Contact Phone: •••-•••-•••• Email: •••••@•••••