Olive oil and betaine gel may ease radiation mouth pain
NCT ID NCT05635929
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial is testing a topical gel and mouthwash made from olive oil, betaine, and xylitol (XCM-OM118) to see if it can reduce severe oral mucositis (painful mouth sores) in head & neck cancer patients receiving radiation. The study will enroll 63 adults and track how many develop severe sores, as well as measure quality of life using patient questionnaires. The goal is to find a simple, non-drug way to ease a common and painful side effect of cancer treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
XCM-OM118 (a gel and mouthwash made from olive oil, betaine, and xylitol)
What this could lead to
If it works, this could offer a simple, non-drug way to prevent severe mouth sores during radiation, improving quality of life for head & neck cancer patients.
What could go wrong
This is a small, early-phase trial with no control group, so results may not be definitive. The treatment may not reduce severe mucositis as hoped.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mucosa Innovations S.L.
RECRUITINGMadrid, Madrid, 28023, Spain
Contact Phone: •••-•••-••••