ORAL MUCOSITIS
Clinical trials for ORAL MUCOSITIS explained in plain language.
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Mouthwash may prevent agonizing side effect of stem cell transplants
Prevention OngoingThis study tests whether a special mouthwash containing N-acetylcysteine can prevent painful mouth sores (oral mucositis) in patients receiving a stem cell transplant. These sores are a common and serious side effect that can cause severe pain and longer hospital stays. The trial…
Matched conditions: ORAL MUCOSITIS
Phase: PHASE3 • Sponsor: Tehran University of Medical Sciences • Aim: Prevention
Last updated Jun 27, 2026 08:10 UTC
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Light therapy may stop painful mouth sores in transplant patients
Prevention OngoingThis study tests if shining a special light inside the mouth, outside the cheek, or both can prevent severe mouth sores in people getting a stem cell transplant. About 78 patients will receive daily light therapy during their transplant stay. The goal is to find the best way to r…
Matched conditions: ORAL MUCOSITIS
Phase: PHASE2 • Sponsor: Brigham and Women's Hospital • Aim: Prevention
Last updated Jun 27, 2026 08:05 UTC
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New drug aims to spare cancer patients from debilitating mouth sores
Symptom relief OngoingThis phase 2 trial tests whether the drug RRx-001 can prevent severe oral mucositis (painful mouth sores) in 216 patients with head and neck cancer receiving standard chemoradiation. Patients are randomly assigned to receive RRx-001 or a placebo alongside their usual treatment. T…
Matched conditions: ORAL MUCOSITIS
Phase: PHASE2 • Sponsor: EpicentRx, Inc. • Aim: Symptom relief
Last updated Jun 28, 2026 00:00 UTC
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Natural mouthwash aimed to soothe radiation mouth sores, but study never started
Symptom relief TerminatedThis study planned to test a mouthwash made from copaíba oil, a natural resin, to prevent and treat painful mouth sores (oral mucositis) in people with oral cancer undergoing radiation. The trial was set to include 40 patients, half using the copaíba mouthwash and half a placebo,…
Matched conditions: ORAL MUCOSITIS
Phase: PHASE2 • Sponsor: Instituto Nacional de Cancer, Brazil • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Could a common herpes drug ease cancer treatment's painful mouth sores?
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether the antiviral drug valacyclovir can prevent or reduce painful mouth sores (oral mucositis) in adults receiving radiotherapy for head and neck cancer. Researchers will give either valacyclovir or a placebo to 84 participants during their radiation treatmen…
Matched conditions: ORAL MUCOSITIS
Phase: PHASE2 • Sponsor: Instituto Oncoclinicas • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC