Natural mouthwash aimed to soothe radiation mouth sores, but study never started

NCT ID NCT06708702

First seen Apr 19, 2026 · Last updated Jun 19, 2026 · Updated 10 times

Summary

This study planned to test a mouthwash made from copaíba oil, a natural resin, to prevent and treat painful mouth sores (oral mucositis) in people with oral cancer undergoing radiation. The trial was set to include 40 patients, half using the copaíba mouthwash and half a placebo, four times a day. However, the study was withdrawn before any participants were enrolled, so no results are available.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Instituto Nacional de Cancer

    Rio de Janeiro, Rio de Janeiro, 20231050, Brazil

  • Instituto Nacional de Cancer, Brazil

    Rio de Janeiro, Rio de Janeiro, 20231050, Brazil

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Copaíba oil (Copaifera Officinalis Resin) mouthwash

What this could lead to

If it had worked, this could have pointed toward a natural mouthwash to ease painful mouth sores during cancer treatment.

What could go wrong

The trial was withdrawn before enrolling any participants, so no results are available. Even if conducted, it was a small early-phase study with only 40 patients, so success was uncertain.

Conditions

The condition(s) this trial relates to.

chemotherapy-induced oral mucositis oral cavity cancer oropharynx cancer stomatitis ulcer disease ulcerative stomatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.