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Depression may worsen GvHD symptoms, new study investigates

NCT ID NCT07314892

Recruiting now Knowledge-focused Sponsor: Medical University of Gdansk Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how depression and other mental health issues impact symptom severity and quality of life in people with graft-versus-host disease (GvHD). Researchers will follow 200 adults with GvHD, using questionnaires to measure psychiatric status and symptoms. The goal is to see if treating depression can help reduce GvHD burden and improve daily life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could show that treating depression improves GvHD symptoms and quality of life, leading to better care guidelines.
What could go wrong
This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may not apply to all GvHD patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Bronchiolitis Obliterans Syndrome chronic graft versus host disease cognitive disorder Cognitive Dysfunction Depression depressive disorder graft versus host disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COGNITIVE IMPAIRMENTS DEPRESSION DISORDERS GVHD GVHD - GRAFT-VERSUS-HOST DISEASE GVHD, CHRONIC QUALITY OF LIFE

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Hematology and Transplantology

    RECRUITING

    Gdansk, Pomeranian Voivodeship, 80-214, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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