DEPRESSION DISORDERS

This study is testing whether a new drug called CYB003 helps reduce depression symptoms when added to a person's current antidepressant medication. It will involve 330 adults with moderate to severe depression who are already taking a stable dose of antidepressants. Participants …

This study is testing if adding a common antidepressant (fluoxetine) to standard immunotherapy helps people with advanced liver or gallbladder cancer who also have depression or anxiety. Researchers want to see if the combination works better at shrinking tumors and helping patie…

This study is testing a new web-based AI tool designed to help detect fatigue and depression in patients with heart conditions. The tool analyzes a person's facial expressions and voice patterns during a short online check-in. Researchers will compare the AI's results to standard…

This study is testing whether a 10-session program combining meditation with neurofeedback technology can help reduce symptoms of depression. Researchers are enrolling 27 adults with moderate depression to try this non-drug approach. The goal is to see if it improves mood, reduce…

This study is testing whether a gentle, non-invasive brain stimulation technique can help teenagers who struggle with non-suicidal self-injury (like cutting) gain better control over their impulses. Researchers will compare real stimulation to a fake (sham) version in 60 teens ag…

This study is testing if an online support program can help teenagers (ages 15-18) who have just left a psychiatric hospital. The program connects teens with trained peer mentors and specialists for virtual meetings and group support over 8 weeks. Researchers want to see if this …

This study aims to find out if heated yoga, regular sauna use, or a mindfulness app can help reduce symptoms of depression. Researchers will enroll 120 adults with moderate depression and assign them to one of these three activities for 12 weeks. They will measure changes in depr…

This study is testing a group mental health program delivered by phone or video call for Canadians aged 55 and older who feel lonely, isolated, anxious, or depressed. It aims to see if this easy-to-access program improves people's ability to cope with difficult feelings and reduc…

This study aims to understand if a patient's mental health, like depression or anxiety, affects how severe their Graft-Versus-Host Disease (GvHD) symptoms are. Researchers will follow 200 adult patients with GvHD, using questionnaires to track their psychiatric status, physical s…

This study aims to create a detailed health profile of 100 adults admitted to a general psychiatric hospital. Researchers will use questionnaires and medical records to measure the severity of mental illness, physical health problems, and treatment history. The goal is to see how…

This study is testing whether an artificial intelligence (AI) tool can reliably measure the severity of depression and anxiety in adults. Researchers will compare the AI's analysis of video interviews to assessments made by human clinicians. The goal is to see if AI can provide c…

This study aims to measure how common and how severe depression is among doctors, nurses, and staff working in heart and chest surgery departments in Baghdad. Researchers will ask 200 healthcare workers to complete a standard depression questionnaire. The goal is to understand th…

This study is testing whether a virtual reality device can detect changes in eye movements in people who have been taking psychiatric medications for at least three months. Researchers want to see if the device can identify patterns linked to medication use, similar to how police…

This study aims to better understand the link between mental health and blood sugar control in people with diabetes. Researchers will follow about 1,800 participants for several years, collecting data on their mood, stress, and glucose levels to create 'digital twin' computer mod…