DEPRESSION DISORDERS

This study compares an enhanced depression treatment (medication management plus cognitive behavioral therapy) to a standard version for 130 youth aged 15-24 with HIV. The goal is to see if the enhanced approach improves depression symptoms and HIV viral control over 72 weeks. Pa…

This study will test if an online therapy program can help people with anxiety and depression in primary care. About 200 adults will either use the online program or receive usual care. The goal is to see if the program improves symptoms and quality of life, and if it can be easi…

This study looks at whether increasing hospital ward visits from twice to four times a day, along with structured talks and simple relaxation exercises, can help lower anxiety in patients waiting for a therapeutic gastrointestinal endoscopy. About 1,000 adults with mild anxiety w…

This study explores whether interactive virtual reality (VR) can help reduce pain, anxiety, and fatigue in people receiving palliative care. Twenty hospitalized adults will use a VR program that lets them interact with a calming natural environment, aiming to distract the brain f…

This study tests a new digital tool called AI-COA® that uses artificial intelligence to measure how severe a person's depression or anxiety is. Researchers will compare the tool's results to standard ratings from doctors over 12 weeks to see if the tool is consistent and sensitiv…

This study checks if an AI software can accurately measure depression and anxiety symptoms in 650 adults with Major Depressive Disorder. Participants will use a computer with a camera and microphone to interact with the AI, which will compare its ratings to those of human experts…

This study aims to see if learning about well-being can positively change how romantic partners think and feel. Researchers will enroll 2000 couples where one partner has mild depression symptoms. Participants will complete online surveys about their mood and relationship satisfa…