One-Dose antibiotic could slash ventilator pneumonia deaths in brain injury patients
NCT ID NCT06819592
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 28 times
Summary
This study tests whether giving a single dose of a common antibiotic soon after a breathing tube is placed can prevent lung infections (pneumonia) and improve survival in ICU patients with severe brain injuries. About 3,300 adults on ventilators due to stroke, trauma, or lack of oxygen will be randomly assigned to receive the antibiotic or a placebo. The goal is to see if early prevention of pneumonia leads to better recovery and lower death rates.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Fiona Stanley Hospital
NOT_YET_RECRUITINGPerth, Western Australia, 6150, Australia
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Nepean Hospital
RECRUITINGKingswood, New South Wales, 2747, Australia
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Princess Alexandra Hospital
RECRUITINGWoolloongabba, Queensland, 4102, Australia
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Royal Brisbane and Women's Hospital
RECRUITINGHerston, Queensland, 4006, Australia
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Royal North Shore Hospital
RECRUITINGSydney, New South Wales, 2000, Australia
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St George Hospital
RECRUITINGKogarah, New South Wales, 2217, Australia
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The Alfred Hospital
NOT_YET_RECRUITINGMelbourne, Victoria, Australia
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The George Institute
NOT_YET_RECRUITINGRandwick, New South Wales, 2031, Australia
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Wellington Hospital
RECRUITINGWellington, New Zealand
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