MYOCARDIAL INFARCTION

This study tests whether spermidine, a natural substance found in foods like wheat germ and soy, can improve heart and muscle health in people aged 65 and older with coronary artery disease. About 180 participants will receive either spermidine or a placebo for a period, and rese…

This study is testing whether adding dried bilberries and oat bran to standard treatment can lower LDL cholesterol and improve exercise capacity in 900 adults with type 2 diabetes or a recent heart attack. Participants take the supplements for three months, and researchers measur…

This study looks at two ways to treat heart attacks in people aged 75 and older who have several blocked heart arteries. One approach only fixes the artery that caused the heart attack, while the other uses a special test to decide which other blockages to open as well. The goal …

This early study tests a new way to prevent heart attacks by freezing dangerous plaque inside heart arteries. The treatment uses a special balloon to cool the plaque, aiming to make it less likely to burst. The study includes 30 people who recently had a heart attack or unstable …

This study tracks over 1,300 heart attack patients who received a procedure called percutaneous coronary intervention (PCI), which opens blocked heart arteries. Researchers want to see if PCI reduces major heart problems like death, another heart attack, or the need for repeat pr…

This study tests whether giving evolocumab (a cholesterol-lowering drug) very early after a heart attack, along with usual care, can reduce the risk of another heart attack, stroke, artery-clearing procedures, or death. About 6,000 adults hospitalized for a heart attack are parti…

This study compares two imaging methods to guide treatment of non-emergency blockages in heart attack patients who have multiple blocked arteries. About 1,800 participants will be randomly assigned to either a new angiography-derived blood flow measurement or standard angiography…

This study tests a new PET heart scan that uses 10 to 100 times less radiation than current methods. It involves 200 adults with known or suspected heart artery disease. Participants get a tiny dose of a radioactive tracer and are scanned for up to 3 hours to see if the images ar…

This study compares a new heart attack diagnosis method that focuses on whether an artery is fully blocked (occlusion) versus the standard method based on ECG changes. Researchers will track 6,000 adults with suspected heart attacks to see if the new approach better predicts arte…

This study tests whether a special heart scan (dynamic SPECT) can accurately detect leftover blockages in heart attack survivors, compared to the current standard invasive test (FFR). About 60 adults with multiple blocked arteries will get both tests. If the scan works well, it c…

This study follows about 3,000 adults in Port-au-Prince, Haiti, for up to 7 years to track heart disease risks like high blood pressure, diabetes, and smoking. Researchers will measure how common these risks are and how they lead to heart attacks, strokes, or heart failure. The g…

This study tests whether giving doctors a special risk score—one that combines a person's genes with things like cholesterol and age—helps them make better decisions to prevent heart disease. About 1,000 people at moderate risk for heart disease but who have never had a heart att…

This study looks at 2000 people who had a heart attack to see if measuring the stiffness of their blood vessels one month later can help predict future problems like heart failure, another heart attack, or stroke. Participants are enrolled within 48 hours of their heart attack an…

This study is gathering health information from 130,000 people who have had a heart attack or unstable chest pain. Researchers will analyze this data to understand which treatments work best and why. The goal is to help doctors and policymakers make better decisions for future pa…

This study looks at whether a new screening system can help find heart complications early in patients at high risk after noncardiac surgery. About 900 adults aged 40-85 will be monitored with blood tests and checkups. The goal is to see if this approach is practical and cost-eff…

This study uses advanced PET/MRI scans to see if a heart attack leads to inflammation in the brain. Researchers will compare 6 people who recently had a heart attack with a control group. The goal is to better understand how the heart and brain are connected, which could lead to …

This study looks at people who had a heart attack but no blocked arteries (MINOCA). Researchers use special imaging to find the real cause, like plaque disruption or artery tears. 450 participants will be followed for up to 10 years to track future heart events. The goal is to be…

This study looks at 15 people who had a heart attack even though their main heart arteries were not blocked. Using special cameras inside the arteries and an MRI of the heart, researchers want to find out what caused the attack. The goal is to learn more about this puzzling type …

This study tests whether a smartphone app that analyzes your voice can spot signs of depression and anxiety in people recovering from a heart attack. About 200 adults in cardiac rehab will use the app alongside their usual care. The goal is to see if the app helps improve emotion…

This study follows over 1,000 people who had a heart attack and received a stent, to see how different outpatient rehab programs affect their long-term health. Researchers track heart-related deaths, repeat heart attacks, strokes, and the need for more procedures. The goal is to …

This study looked at 160 people with heart disease who received either a biolimus-eluting or everolimus-eluting stent to open blocked arteries. The goal was to compare how well the blood vessel healed inside the stent at one and three months after placement, using a special camer…

This study follows 1,599 people who had their first heart attack to see how the heart's shape and function change over time. Researchers want to understand which patterns of remodeling lead to heart failure. Participants are from several Minnesota counties and are not receiving a…

This long-term study aims to understand how early, hidden signs of heart disease develop and predict future heart attacks, strokes, and heart failure. It follows over 6,400 adults from four different ethnic groups who started the study with no known heart disease. Researchers use…