Heart attack patients may get safer blood thinners thanks to genetic test

NCT ID NCT05577988

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a genetic test can help choose a safer blood thinner for people who have had a heart attack. After one month on two blood thinners, some patients will switch to a single, lower-potency drug based on their genetic profile. The goal is to see if this approach causes fewer bleeding problems while still preventing future heart attacks. About 2,468 participants will be followed for one year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
aspirin or clopidogrel (guided by genetic test)
What this could lead to
If successful, this could lead to a personalized approach that lowers bleeding risk after a heart attack without increasing the chance of another heart attack or stroke.
What could go wrong
This is a large Phase 3 trial, but the genetic testing approach is complex and may not work for everyone. There is still a risk of bleeding or clotting events.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hopital Pitié Salpetrière

    RECRUITING

    Paris, IDF, 75013, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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