Could dropping aspirin after a heart attack be safer?
NCT ID NCT07257198
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether taking only the blood thinner ticagrelor (instead of the usual combination of ticagrelor plus aspirin) can reduce bleeding after a heart attack. It involves 2,570 adults who had a heart attack but did not receive stents or bypass surgery. Participants will take either ticagrelor plus a placebo or ticagrelor plus aspirin for 12 months, and researchers will compare bleeding events and major heart problems between the two groups.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Ticagrelor (a blood thinner) plus a placebo, compared to ticagrelor plus aspirin
- What this could lead to
- If successful, this could show that using only ticagrelor after a heart attack lowers bleeding risk while still preventing future heart problems, leading to a safer treatment option.
- What could go wrong
- This is a large Phase 3 trial, but it only includes patients who did not receive stents or bypass surgery, so results may not apply to everyone. There is still a risk that ticagrelor alone may not prevent heart attacks or strokes as well as the standard combination.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Montreal Heart Institute
RECRUITINGMontreal, Quebec, H1Y2P3, Canada
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