Zapping the heart with radiation to stop deadly rhythms

NCT ID NCT04162171

Recruiting now Disease control Sponsor: John Sapp Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a noninvasive radiation treatment (SBRT) for people with ventricular tachycardia, a dangerous heart rhythm that can cause sudden death. The 12 participants have structural heart disease and have not been helped by standard treatments like drugs or catheter ablation. The goal is to see if precisely targeted radiation can reduce these abnormal heart rhythms while sparing healthy tissue.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: radiation (stereotactic body radiotherapy)
What this could lead to: If it works, this could offer a noninvasive treatment option for dangerous heart rhythms when drugs and catheter ablation have failed.
What could go wrong: This is a very small early study (12 people) with no control group, so results may not apply widely. Radiation to the heart carries risks like inflammation, lung damage, or heart failure.

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Conditions

The condition(s) this trial relates to.

heart disorder myocardial infarction ventricular tachycardia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART DISEASE STRUCTURAL DISORDER MYOCARDIAL INFARCTION VENTRICULAR TACHYCARDIA

Contacts and locations

Locations

Nova Scotia Health Authority
RECRUITING

Halifax, Nova Scotia, B3H 3A7, Canada

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