Could less blood pressure medicine save more lives in heart shock?

NCT ID NCT05168462

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether using less of the drug noradrenaline, by aiming for a lower blood pressure target (55 mmHg instead of 65 mmHg), can improve survival and reduce severe kidney failure in people with cardiogenic shock after a heart attack. About 776 adults will be randomly assigned to one of two blood pressure goals. The main outcomes are death and need for kidney dialysis within 30 days.

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Conditions

The condition(s) this trial relates to.

acute myocardial infarction cardiogenic shock myocardial infarction Shock, Cardiogenic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Amsterdam UMC, location AMC

    RECRUITING

    Amsterdam, 1105AZ, Netherlands

    Contact Email: •••••@•••••