Could less blood pressure medicine save more lives in heart shock?

NCT ID NCT05168462

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether using less of the drug noradrenaline, by aiming for a lower blood pressure target (55 mmHg instead of 65 mmHg), can improve survival and reduce severe kidney failure in people with cardiogenic shock after a heart attack. About 776 adults will be randomly assigned to one of two blood pressure goals. The main outcomes are death and need for kidney dialysis within 30 days.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Amsterdam UMC, location AMC

    RECRUITING

    Amsterdam, 1105AZ, Netherlands

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