Tiny blood samples, big clues: can we predict clots in newborn heart surgery?

NCT ID NCT06434207

First seen Nov 12, 2025 · Last updated Jun 22, 2026 · Updated 29 times

Summary

This study will collect leftover blood samples from 10 newborns with severe heart defects who have surgery at Boston Children's Hospital. Researchers want to understand why these babies are more likely to develop dangerous blood clots after surgery. They will look at tiny molecules called microRNAs in the blood to find patterns linked to clotting and inflammation.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could point toward ways to predict or prevent dangerous blood clots in newborns with heart disease.

What could go wrong

This is a very small, early observational study with only 10 participants. It is not testing a treatment, so it may not lead to direct changes in care.

Conditions

The condition(s) this trial relates to.

congenital heart disease thrombotic disease univentricular heart

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.