SINGLE VENTRICLE
Clinical trials for SINGLE VENTRICLE explained in plain language.
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Stem cell injection aims to strengthen Children's hearts after major surgery
Disease control Recruiting nowThis study tests whether injecting a child's own heart stem cells (JRM-001) into the heart after reconstructive surgery can improve heart function. It includes 40 children with a single ventricle heart defect who are scheduled for a second or third stage surgery. The goal is to s…
Matched conditions: SINGLE VENTRICLE
Phase: PHASE3 • Sponsor: Metcela Inc. • Aim: Disease control
Last updated May 17, 2026 02:56 UTC
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Digital fitness boost for kids with rare heart condition
Symptom relief Recruiting nowThis study tests whether a home-based digital exercise program can help children aged 10-17 with Fontan circulation (a heart condition) become more physically active and fit. Participants will wear an activity tracker for 12 months and complete fitness tests. Half will also recei…
Matched conditions: SINGLE VENTRICLE
Phase: NA • Sponsor: Children's Hospital of Philadelphia • Aim: Symptom relief
Last updated May 17, 2026 02:59 UTC
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Heart rehab trial aims to boost steps and strength in fontan failure patients
Symptom relief Recruiting nowThis study tests whether a cardiac rehabilitation program can help adults with Fontan failure walk more each day and improve their exercise ability and quality of life. About 50 participants will either join the rehab program or receive usual care. The goal is to see if rehab red…
Matched conditions: SINGLE VENTRICLE
Phase: NA • Sponsor: Stanford University • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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Tiny hearts, big questions: why do newborns with heart defects get blood clots?
Knowledge-focused Recruiting nowThis study looks at why newborns with severe heart disease are more likely to develop dangerous blood clots after heart surgery. Researchers will collect blood samples from 10 babies to study tiny molecules called microRNAs that may control clotting. The goal is to better underst…
Matched conditions: SINGLE VENTRICLE
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 03:10 UTC
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Infant heart drug under the microscope: new study aims to uncover how digoxin works
Knowledge-focused Recruiting nowThis study looks at how the heart medication digoxin is processed by the bodies of infants with a rare heart condition called single ventricle heart disease. About 20 babies under 6 months old will participate, and researchers will collect blood samples during routine care to mea…
Matched conditions: SINGLE VENTRICLE
Phase: PHASE1, PHASE2 • Sponsor: Duke University • Aim: Knowledge-focused
Last updated May 17, 2026 03:10 UTC
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New registry tracks heart drug use in adults born with heart defects
Knowledge-focused Recruiting nowThis study is a global registry that will collect information from 400 adults with congenital heart disease who are taking a type of diabetes drug called SGLT2 inhibitors. The goal is to understand how these drugs are prescribed, how safe they are, and whether they help with hear…
Matched conditions: SINGLE VENTRICLE
Sponsor: Leiden University Medical Center • Aim: Knowledge-focused
Last updated May 12, 2026 13:39 UTC
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New 3D heart scan could improve care for kids born with one ventricle
Knowledge-focused Recruiting nowThis study is testing a new 3D ultrasound technique to see if it can accurately measure heart size and function in children and young adults born with a single ventricle (a heart with only one pumping chamber). Researchers will compare this method to standard tests like echocardi…
Matched conditions: SINGLE VENTRICLE
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated May 07, 2026 18:42 UTC