SINGLE-VENTRICLE

This study is testing whether a supervised cardiac rehabilitation program can help adults with Fontan heart failure get stronger and feel better. Researchers will compare the rehab program to usual medical care in 50 participants. They will measure changes in daily activity, exer…

This study is testing whether injecting a child's own heart stem cells directly into their heart arteries after major reconstructive surgery can help improve their heart's pumping strength and overall function. It involves 40 children born with severe heart defects where only one…

This study is testing a new 3D ultrasound imaging technique to better measure heart size and function in children and young adults born with only one working heart pumping chamber. Researchers will compare this new method against the current gold standard, cardiac MRI, to see if …

This study aims to understand why newborns with severe congenital heart disease are at high risk for dangerous blood clots after surgery. Researchers will collect blood samples from 10 newborns to analyze tiny molecules that may control clotting. The goal is to uncover the biolog…

This international registry aims to gather real-world information on how a class of drugs called SGLT2 inhibitors is being used in adults born with heart defects. It will track 400 patients who are already prescribed this medication to see how they tolerate it and if it helps imp…

This study aims to learn how infants born with a severe heart defect called single ventricle disease process the heart medication digoxin. Researchers will collect small blood samples from up to 20 infants during their regular medical care to measure drug levels and heart-related…