Heart drug hope: diabetes meds may help adults born with heart defects
NCT ID NCT06932081
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This international registry is tracking 400 adults with congenital heart disease who are taking SGLT2 inhibitors, a type of diabetes medication that also benefits the heart. Researchers want to see how these drugs are being prescribed, how well they are tolerated, and whether they improve heart failure outcomes. The study is purely observational, meaning it collects real-world data without assigning treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
SGLT2 inhibitors (a class of diabetes drugs that help the heart and kidneys)
What this could lead to
If successful, this registry could show that SGLT2 inhibitors are safe and helpful for adults with congenital heart disease, potentially leading to better heart failure management.
What could go wrong
This is an observational registry, not a controlled trial, so it cannot prove cause and effect. Results may be influenced by other factors, and the study is relatively small (400 participants).
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Amsterdam University Medical Center
RECRUITINGAmsterdam, Netherlands
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Barts Heart Centre
RECRUITINGLondon, United Kingdom
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Golden Jubilee University National Hospital
RECRUITINGGlasgow, United Kingdom
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Heart Center Duisburg (Evangelical Hospital Niederrhein)
RECRUITINGDuisburg, Germany
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Helen DeVos Children's Hospital
RECRUITINGGrand Rapids, Michigan, 49503, United States
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Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21205, United States
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Leiden University Medical Center (LUMC)
RECRUITINGLeiden, South Holland, 2333ZA, Netherlands
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Mount Sinai Fuster Heart Hospital
RECRUITINGNew York, New York, 10029, United States
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University Hospital of Wales
RECRUITINGCardiff, United Kingdom
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University Medical Center Utrecht
RECRUITINGUtrecht, Netherlands
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Zan Mitrev Clinic
RECRUITINGSkopje, North Macedonia
Contact