Could a child's own stem cells strengthen a weak heart after surgery?

NCT ID NCT02781922

First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 37 times

Summary

This study tests whether injecting a child's own heart stem cells (JRM-001) after reconstructive surgery can improve heart function in children with single ventricle heart defects. About 40 children scheduled for Glenn or Fontan surgery will receive either the stem cells or a placebo. The main goal is to see if the treatment boosts the heart's pumping ability, measured by MRI.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Kanagawa Children's Medical Center

    RECRUITING

    Kanagawa, Japan

  • Okayama University Hospital

    RECRUITING

    Okayama, Japan

  • Saitama Prefectural Children's Medical Center

    RECRUITING

    Saitama, Japan

  • Shizuoka Children's Hospital

    RECRUITING

    Shizuoka, Japan

Conditions

Explore the condition pages connected to this study.