THROMBOSIS

This study tests whether patients with a heart pump (LVAD) can safely stop taking aspirin while continuing warfarin. The goal is to reduce bleeding problems without increasing dangerous clots. About 370 participants will be randomly assigned to receive either aspirin or a placebo…

This study tests a needle-free connector with anti-reflux technology, a special stopper that prevents blood from flowing back into IV catheters. The goal is to see if it reduces complications like blockages, infections, and pain compared to standard connectors. The trial will inv…

This Phase 2 trial tests whether a single dose of gruticibart, a monoclonal antibody, can prevent blood clots that often form when a central venous catheter is placed. About 90 adults getting a catheter will receive either the drug or a placebo. The goal is to see if gruticibart …

This study looks at how well platelets work in patients on a life-support machine called ECMO, which helps people with severe lung or heart problems. The goal is to understand why these patients often have dangerous bleeding. Researchers will measure platelet function over time a…

This study aims to find out how often hospitalized patients develop blood clots related to common catheters (PICC, FICC, CICC, and midline). Researchers will use ultrasound to check 500 adults who have had a catheter for at least 7 days. The goal is to better understand how many …

This study follows 700 cancer patients who take blood thinners and are scheduled for surgery or medical procedures. Researchers will track how often major bleeding or clotting events occur within 30 days after the procedure. The goal is to see if current blood thinner management …

This study looks back at the medical records of 50 adult ICU patients with COVID-19 who needed a life-support machine called ECMO. The goal is to understand how often bleeding and dangerous blood clots happen, and how blood transfusions and blood thinners affect their care. The f…

This study looks at how artificial sweeteners (saccharin, sucralose) and a natural one (erythritol) affect blood sugar control, blood clotting, and heart disease risk in 80 adults with prediabetes. Participants will be randomly assigned to take one sweetener or water for two week…