Could LVAD patients ditch aspirin? new trial aims to find out

NCT ID NCT07644247

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether patients with a heart pump (LVAD) can safely stop taking aspirin while continuing warfarin. The goal is to reduce bleeding problems without increasing dangerous clots. About 370 participants will be randomly assigned to receive either aspirin or a placebo, and researchers will track strokes, pump clots, and major bleeding for one year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
aspirin
What this could lead to
If successful, this could simplify medication for LVAD patients by safely removing aspirin, reducing bleeding risks while still preventing clots.
What could go wrong
This is a Phase 4 trial, but it's not yet recruiting. Removing aspirin might increase the risk of dangerous clots or strokes, and results may not apply to other LVAD devices.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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