China National Center For Cardiovascular Diseases

This study tests whether a home-based cardiac rehab program delivered through a mobile app can reduce plaque buildup in the heart arteries of people with mild to moderate blockages. 176 participants will either get the app-based program (with exercise plans, diet advice, and ment…

This study tests a new way to guide catheter ablation for atrial fibrillation (AF), a common heart rhythm problem. The technique uses unipolar voltage mapping to find specific electrical signals (QS potentials) that may help keep AF going. Researchers will compare this personaliz…

This study looks at whether people with atrial fibrillation (AF) can safely stop taking blood thinners after a successful catheter ablation procedure. About 3,160 adults who have been free of AF for 6 to 12 months after ablation will be randomly assigned to either continue or sto…

This study compares a new procedure called pulsed field ablation (PFA) to standard treatment for atrial fibrillation, a common heart rhythm problem that raises stroke risk. About 1,574 adults who need catheter ablation will be randomly assigned to receive PFA or standard care. Th…

This study tests a new surgical method for heart bypass surgery that avoids touching the aorta, aiming to reduce brain complications like silent strokes. About 380 adults with coronary artery disease will be randomly assigned to either the new no-touch technique or the standard m…

This study looks at two types of stents (small mesh tubes) placed in heart arteries to keep them open. It focuses on patients with acute coronary syndrome who also have a high risk of bleeding. The goal is to see how well the blood vessel heals around the stent one month after th…

This study tests a medicine called ademetionine in 44 adults with a heart condition that blocks blood flow. Participants will take either the medicine or a placebo for 16 weeks. Researchers will check if it helps with exercise, symptoms, and heart function.

This early-stage study tests whether empagliflozin, a drug used for diabetes, can help people with pulmonary arterial hypertension (PAH). About 72 adults will take either the drug or a placebo daily for 12 weeks. Researchers will check if it lowers lung blood pressure and improve…

This study tests whether a daily pill called engagliflozin (a type of SGLT2 inhibitor) can improve heart function in people who have high blood pressure and early signs of heart failure but do not have diabetes. About 120 adults will receive either the drug or a placebo for 6 mon…

This study tests whether artificial intelligence (AI) can help doctors in China pick better blood pressure medications for their patients. Over 2,000 adults with high blood pressure will be treated at primary care clinics. Some clinics will use AI software that considers patient …

This study is testing a mini-program (like a smartphone app) that gives personalized exercise advice to people with high blood pressure, high blood sugar, high cholesterol, and high uric acid. Over six months, 100 participants will use the app to increase their daily steps and ph…

This study tests whether an AI-powered smartphone app, called 'Smart family doctor,' can help people who have had heart bypass surgery or stents better control their blood pressure, diabetes, and cholesterol. About 536 adults who already have these conditions will use the app to …

This study tests whether an artificial intelligence (AI) smartphone app can help adults with coronary heart disease exercise safely at home after hospital discharge. About 200 low-risk patients will either use the AI platform with a wristband or receive standard care. The goal is…

This study compares two blood-thinning strategies after a combined heart bypass and endarterectomy procedure. About 202 adults with widespread coronary artery disease will receive either standard dual antiplatelet therapy or that therapy plus warfarin. The goal is to see if addin…

This study is testing whether an AI-driven system called SMART-CHD can improve outcomes for adults aged 18-45 with premature coronary artery disease. Participants will use a mobile app and wearable sensors to track their health and receive personalized guidance. The goal is to se…

This study tests whether Xuesaitong soft capsules, an herbal medicine, can reduce inflammation and other risk factors in 240 adults with stable coronary heart disease. Participants take either the capsule or a placebo daily for 12 weeks. The main goal is to see if the capsule low…

This study tests a new technology called IVUS-FFR that uses ultrasound images from inside heart arteries to quickly check if a blockage is serious enough to need a stent. Unlike the current standard test, it doesn't require an extra pressure wire or medication that can cause disc…

This study tests whether an artificial intelligence (AI) algorithm can screen for coronary artery disease (CAD) by analyzing facial images. Researchers will enroll 1,392 high-risk adults (those with diabetes, high blood pressure, or over 65) and use the AI to classify them as hig…

This study tests whether two traditional Chinese medicines—Compound Danshen Dripping Pills and Qishen Yiqi Dripping Pills—can reduce chest pain and improve quality of life in elderly patients (75-90 years old) with coronary heart disease who still have symptoms despite standard t…

This observational study will analyze data from 3,000 people with complex congenital heart disease who have had or will have heart surgery in China. Researchers aim to identify key risk factors affecting recovery and build a quality control system to improve surgical care. Partic…

This study is testing a new way to measure blood flow in the heart's arteries using ultrasound, without needing special wires or drugs. Researchers will follow about 500 people with coronary artery disease for one year to see if this measurement can predict serious heart events l…

This study will follow at least 700 people with pulmonary hypertension to track side effects and deaths related to targeted medications. Participants will be checked every 6 months using a computer system. The goal is to better understand the safety of these drugs in real-world u…

This study tests whether artificial intelligence can evaluate how well surgeons perform a key step in heart bypass surgery. Researchers will compare AI scores to those from human experts. The trial involves 284 patients undergoing bypass grafting and aims to see if AI can reliabl…