Could a simple heart procedure free millions from daily blood thinners?

NCT ID NCT06615596

Recruiting now Disease control Sponsor: China National Center for Cardiovascular Diseases Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether people with atrial fibrillation (AF) can safely stop taking blood thinners after a successful catheter ablation procedure. About 3,160 adults who have been free of AF for 6 to 12 months after ablation will be randomly assigned to either continue or stop their blood thinners. Smart wearable devices will monitor for any return of AF, and participants will be followed for two years to compare rates of stroke, bleeding, and other events.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: discontinuation of anticoagulation therapy
What this could lead to: If successful, this could change guidelines so that many AF patients can safely stop taking blood thinners after ablation, reducing bleeding risks.
What could go wrong: This is an early-phase study, and stopping blood thinners may increase the risk of stroke in some patients. The results may not apply to everyone with AF.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION (AF)

Contacts and locations

Locations

Beijing Anzhen Hospital
NOT_YET_RECRUITING

Beijing, Beijing Municipality, 100011, China
Brigham and Women Hospital
NOT_YET_RECRUITING

Boston, Massachusetts, 02115, United States
Fuwai Central China Cardiovascular Hospital
NOT_YET_RECRUITING

Zhengzhou, Henan, China
Fuwai Hospital
RECRUITING

Beijing, Beijing Municipality, 100037, China
Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen
RECRUITING

Shenzhen, Guangdong, China
Shanghai Chest Hospital
NOT_YET_RECRUITING

Shanghai, Shanghai Municipality, China
Shanxi Cardiovascular Hospital (Shanxi Cardiovascular Research Institute)
NOT_YET_RECRUITING

Taiyuan, Shanxi, China
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, China
The First Affiliated Hospital, Sun Yat-sen University
NOT_YET_RECRUITING

Guangzhou, Guangdong, China
West China Hospital, Sichuan University
NOT_YET_RECRUITING

Chengdu, Sichuan, China
Wuhan Asia Heart Hospital
RECRUITING

Wuhan, Hubei, China
Yunnan Fuwai Cardiovascular Hospital
NOT_YET_RECRUITING

Kunming, Yunnan, China

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