Could a simple heart procedure free millions from daily blood thinners?
NCT ID NCT06615596
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether people with atrial fibrillation (AF) can safely stop taking blood thinners after a successful catheter ablation procedure. About 3,160 adults who have been free of AF for 6 to 12 months after ablation will be randomly assigned to either continue or stop their blood thinners. Smart wearable devices will monitor for any return of AF, and participants will be followed for two years to compare rates of stroke, bleeding, and other events.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
discontinuation of anticoagulation therapy
What this could lead to
If successful, this could change guidelines so that many AF patients can safely stop taking blood thinners after ablation, reducing bleeding risks.
What could go wrong
This is an early-phase study, and stopping blood thinners may increase the risk of stroke in some patients. The results may not apply to everyone with AF.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beijing Anzhen Hospital
NOT_YET_RECRUITINGBeijing, Beijing Municipality, 100011, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Brigham and Women Hospital
NOT_YET_RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Fuwai Central China Cardiovascular Hospital
NOT_YET_RECRUITINGZhengzhou, Henan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Fuwai Hospital
RECRUITINGBeijing, Beijing Municipality, 100037, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen
RECRUITINGShenzhen, Guangdong, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-••••
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Shanghai Chest Hospital
NOT_YET_RECRUITINGShanghai, Shanghai Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shanxi Cardiovascular Hospital (Shanxi Cardiovascular Research Institute)
NOT_YET_RECRUITINGTaiyuan, Shanxi, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital, Sun Yat-sen University
NOT_YET_RECRUITINGGuangzhou, Guangdong, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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West China Hospital, Sichuan University
NOT_YET_RECRUITINGChengdu, Sichuan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Wuhan Asia Heart Hospital
RECRUITINGWuhan, Hubei, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Yunnan Fuwai Cardiovascular Hospital
NOT_YET_RECRUITINGKunming, Yunnan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••