Sugar substitutes under scrutiny: new study targets heart risks in prediabetes

NCT ID NCT07377097

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how artificial sweeteners (saccharin, sucralose) and a natural one (erythritol) affect blood sugar control, blood clotting, and heart disease risk in 80 adults with prediabetes. Participants will be randomly assigned to take one sweetener or water for two weeks. Researchers will measure changes in glucose tolerance, gut bacteria, and immune cells to see if these sweeteners might be harmful.

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome cardiovascular disorder Insulin Resistance metabolic syndrome X prediabetes syndrome thrombophilia thrombotic disease type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••