THROMBOSIS

This study aims to find the best platelet transfusion level for extremely premature babies (born at 23-27 weeks). Researchers will compare whether using a lower platelet count as the trigger for transfusion is as safe as using a higher trigger. The goal is to improve survival wit…

This study is testing whether a new artificial intelligence (AI) tool can help doctors more completely diagnose the many complications that can occur with rheumatoid arthritis (RA), such as lung, heart, or thyroid problems. Researchers will give doctors AI-generated predictions a…

This study is testing a new type of heart scan to see if it can detect blood clots inside the heart's arteries. The goal is to better understand what caused a patient's heart attack, as not all heart attacks are caused by clots. Researchers will enroll 80 people who recently had …

This early-stage study is testing a new imaging tracer called 64Cu-FBP8 to see if it can safely and accurately detect blood clots throughout the body using a PET-MR scan. Researchers are enrolling 165 healthy volunteers and patients with conditions like atrial fibrillation, COVID…

This large UK study aims to find the best way to prevent dangerous blood clots in people who get a leg cast or splint after an injury. It will test if taking pills is as effective and easier than the standard daily injections for high-risk patients, and if any medication is bette…

This study aims to understand how platelets—the blood cells responsible for clotting—normally function in healthy adults. Researchers will follow 400 healthy volunteers for 10 years, collecting blood samples and health information every six months. The goal is to see how diet, ex…

This study aims to understand where blood clots come from and what role they play in causing different types of stroke. Researchers will use a new imaging tracer, called 18F-GP1, to take pictures of active blood clots in the brains of 120 adults who recently had a stroke. The goa…

This study aims to understand why newborns with severe congenital heart disease are at high risk for dangerous blood clots after surgery. Researchers will collect blood samples from 10 newborns to analyze tiny molecules that may control clotting. The goal is to uncover the biolog…

This study aims to understand if a specific blood test (anti-factor Xa activity) can predict the risk of dangerous blood clots in critically ill patients in the intensive care unit. Researchers will observe 1,300 patients to see how the test results relate to clot formation, blee…

This study aims to create a long-term collection of biological samples to help researchers better understand heart and blood vessel diseases. It will collect blood, urine, and stool samples from 500 adults who have or are at risk for these conditions. The goal is to build a share…

This study aims to collect long-term safety and effectiveness data on treatments for various non-cancerous blood disorders, including hemophilia, von Willebrand disease, and platelet disorders. It will follow up to 3,000 participants for at least 15 years to see how newer, FDA-ap…

This study is looking for a better way to predict which cancer patients might have serious bleeding while taking blood thinners for a clot. Researchers will measure a specific blood test (thrombin generation) in 212 patients with cancer and a recent blood clot. They will see if t…