New scan could spot hidden blood clots without needles or surgery

NCT ID NCT03830320

Recruiting now Diagnosis Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study is testing a new radioactive tracer called 64Cu-FBP8 that lights up blood clots on a special PET-MR scan. Researchers want to see if it can safely and accurately detect clots in people with atrial fibrillation, COVID-19, or cancer. The study involves 165 participants and aims to find a non-invasive alternative to current clot-detection methods.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 64Cu-FBP8 (a radioactive tracer)
What this could lead to: If successful, this could provide a safer, whole-body scan to detect dangerous blood clots without invasive procedures.
What could go wrong: This is a very early Phase 1 study focused on safety and imaging accuracy. The tracer may not prove reliable enough for routine use, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation cancer COVID-19 neoplasm thrombotic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION CANCER COVID-19 THROMBOSIS

Contacts and locations

Locations

Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States

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