Could blood thinners stop a second stroke? new trial investigates

NCT ID NCT06486792

Recruiting now Disease control Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at people over 65 who recently had a stroke with no clear cause. Doctors suspect they may have hidden atrial fibrillation (an irregular heartbeat) not caught in the hospital. The trial compares two treatments: a blood thinner (apixaban) or aspirin, to see which better prevents another stroke or blood clots. About 1,148 participants will be monitored for up to 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Apixaban (a blood thinner) or aspirin
What this could lead to: If successful, this could show that using blood thinners early after a stroke of unknown cause reduces the risk of another stroke.
What could go wrong: This is a Phase 4 trial, but the benefit-risk balance of blood thinners versus aspirin in this specific group is still unproven. Blood thinners carry a risk of bleeding.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation cerebral infarction ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION CEREBRAL INFARCTION ISCHEMIC STROKE STROKE

Contacts and locations

Locations

Bichat Hospital
RECRUITING

Paris, Paris, 75018, France

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