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Massive global trial aims to find best stroke treatments

NCT ID NCT06352632

Recruiting now Disease control Sponsor: The George Institute Source: ClinicalTrials.gov ↗

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This trial is testing several different treatments for stroke, including different doses of a clot-busting drug called tenecteplase and blood pressure management strategies. It aims to find which treatments or combinations work best to improve recovery and reduce disability. The study will include 20,000 adults diagnosed with stroke from hospitals around the world.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
tenecteplase (clot-busting drug) and blood pressure management
What this could lead to
If successful, this trial could identify the most effective combination of treatments to improve recovery and reduce disability after a stroke, potentially changing global stroke care guidelines.
What could go wrong
This is a large, complex trial testing many treatments at once, so results may take years and some approaches may not prove better than current care. Bleeding risk from clot-busting drugs is a known concern.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

intracerebral hemorrhage Ischemic Stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STROKE

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The George Institute for Global Health

    RECRUITING

    Sydney, New South Wales, 2005, Australia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Calgary

    RECRUITING

    Calgary, Alberta, T2N 1N4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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