Could a brain pacemaker help stroke survivors move again?
NCT ID NCT05701280
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether deep brain stimulation (DBS) combined with physical therapy can improve arm weakness in people who had a stroke 1 to 6 years ago. About 202 participants will receive either DBS plus rehab or rehab alone. The goal is to see if the treatment safely restores arm movement and function.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Deep brain stimulation (DBS) device
What this could lead to
If successful, this could offer a new way to improve arm movement and daily function for people with long-term weakness after a stroke.
What could go wrong
This is an early pivotal study with 202 participants, so results may not apply to everyone. DBS surgery carries risks like infection or bleeding, and the treatment may not work for all.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Barrow Neurological Institute (BNI)
RECRUITINGPhoenix, Arizona, 85013, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Johns Hopkins School of Medicine
RECRUITINGBaltimore, Maryland, 21218, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55906, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic Florida
RECRUITINGJacksonville, Florida, 32224, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Medical University of South Carolina (MUSC)
TERMINATEDCharleston, South Carolina, 29425, United States
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NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Rhode Island Hospital
RECRUITINGProvidence, Rhode Island, 02903, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Thomas Jefferson University
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••