STROKE

This study provides an 84-year-old man who had a severe ischemic stroke with access to an experimental treatment using his own stem cells (HB-adMSCs). The goal is to see if the treatment is safe and may help control the damage from the stroke. The patient received the cells after…

This study looks at how managing blood pressure during a clot retrieval procedure for stroke affects recovery. About 550 people having emergency clot removal will be followed to see if different blood pressure targets improve disability and survival at 90 days. The goal is to fin…

This study tests whether a video-based telehealth program can help stroke survivors better manage their blood pressure after leaving the hospital. About 542 adults who had a stroke or mini-stroke and have high blood pressure will take part. The program uses remote check-ins and e…

This study compares a new blood thinner called abelacimab to the standard drug rivaroxaban in about 1,300 people with atrial fibrillation (an irregular heartbeat) who are at moderate-to-high risk of stroke. The main goal is to see if abelacimab causes fewer serious or nuisance bl…

This study tests a smart wearable airbag that inflates when it senses a fall, cushioning the impact to prevent injury. Researchers are enrolling 200 people at high risk of falling, including those with stroke, Parkinson's, or leg amputation. The goal is to see if the device works…

This study tests a healthy lifestyle program designed for people who have had a stroke. The program focuses on weight loss and increasing physical activity. Researchers will track 65 participants for 12 months to see if the program helps them achieve lasting health improvements.

This study looks at whether treating obstructive sleep apnea with a CPAP machine, starting soon after a stroke, can lower the chance of having another stroke, a heart attack, or dying within 6 months. Over 3,000 people who had a stroke are taking part. The goal is to see if sleep…

This study tests a new device (Laminar LAAC) to close off a small pouch in the heart called the left atrial appendage in people with non-valvular atrial fibrillation. The goal is to reduce the risk of stroke and blood clots. About 1,500 participants will be randomly assigned to g…

This study compares the WATCHMAN FLX device, which closes off a part of the heart to prevent clots, with standard blood thinners (NOACs) in 3,000 people with non-valvular atrial fibrillation. The goal is to see if the device is as good as medication at preventing stroke and death…

This study tests a safe, non-invasive treatment called distant ischemic adaptation for people who have had a stroke or have small vessel brain disease. The treatment involves briefly inflating a blood pressure cuff on the arm to trigger the body's natural protection. Researchers …

This study observes over 600 people with atrial fibrillation who received the Amulet device to close a part of the heart called the left atrial appendage. The goal is to see how well the device prevents strokes and bleeding in everyday medical practice. Participants are followed …

This study tests whether 8 weeks of a blood thinner (DOAC) or antiplatelet medication works better to prevent clots on a device placed in the heart's left atrial appendage. The device is used to reduce stroke risk in people with atrial fibrillation. The trial involves 510 adults …

This study tests whether virtual group visits can help people with type 2 diabetes and at least one heart-related condition (like high blood pressure or obesity) improve their blood sugar control. About 720 adults with high A1C levels will take part. The main goal is to see if th…

This study tests whether exercise, brain training, or both can improve physical and mental abilities in adults 60 and older who have had a stroke and also have high blood pressure or diabetes. About 444 participants from community health centers in five Chinese cities will take p…

This study compares two ways to prevent strokes in people with atrial fibrillation (an irregular heartbeat). One group gets a device called the Amulet that plugs a small pouch in the heart where clots can form. The other group takes standard blood-thinning medication (NOACs). The…

This study tests whether combining two types of electrical stimulation can improve arm and hand function in people who had a stroke at least six months ago. The therapy uses a robotic device with muscle stimulation plus spinal stimulation. The goal is to see if this approach help…

This study aimed to test whether donated umbilical cord blood could help adults with stroke or spinal cord injury. It planned to measure changes in disability and track side effects. However, the trial was withdrawn before enrolling any participants, so no results are available.

This study tests whether newer blood thinners (rivaroxaban or ticagrelor) are better than the standard drug clopidogrel at preventing stroke or death in people with severely narrowed brain arteries. About 1,683 participants who recently had a stroke due to 70-99% narrowing of a m…

This study looks at a device called the AMPLATZER PFO Occluder, which is used to close a small hole in the heart (PFO) that can cause strokes. Over 1,200 people who had a stroke in the past 18 months and have a PFO took part. The goal is to see if the device is safe and helps pre…

This study tests whether high-intensity interval training (HIIT) on a stationary bike can improve heart rate variability—a key sign of good recovery—in people who recently had a stroke. About 50 patients in the early stages of recovery will either do HIIT or low-intensity exercis…

This study tests a new device (Occlutech Flex II PFO Occluder) to close a small hole in the heart called a PFO, which can cause strokes. About 450 people who have had a stroke from an unknown cause and have a PFO will receive either the new device or a standard one. The goal is t…

This study looks at whether adding a protein drink after exercise helps stroke survivors build more muscle and get stronger. About 93 people who had a stroke at least 3 months ago will take part. Half will get a protein supplement after their workouts, and the other half will get…

This study tests whether giving evolocumab (a cholesterol-lowering drug) very early after a heart attack, along with usual care, can reduce the risk of another heart attack, stroke, artery-clearing procedures, or death. About 6,000 adults hospitalized for a heart attack are parti…

This study looks at a device called the GORE® CARDIOFORM Septal Occluder, which is used to close a small hole in the heart (PFO) in people who have had a stroke with no clear cause. The goal is to see if the device safely prevents future strokes. About 300 people in Japan will be…

This study tests whether people with atrial fibrillation can take just one blood thinner or aspirin after getting a WATCHMAN FLX Pro device, instead of the usual two-drug plan. About 1,857 participants will be followed for 6 months to see if the simpler plans are as safe and effe…

This study tests whether a water-resistant, wireless ECG patch worn for 7 days can find more cases of hidden atrial fibrillation (an irregular heartbeat) in people who recently had a stroke or mini-stroke than the usual 24-hour Holter monitor. About 320 adults with no clear cause…

This study tests whether a special CT scan done in the treatment room can accurately detect brain bleeding in stroke patients. If it works, it could speed up diagnosis and treatment by eliminating the need for a separate scan. The study involves 252 adults with stroke symptoms an…

This study tests whether sending a friendly letter from a pharmacist can motivate more adults to get their flu or travel vaccines. About 20,000 people in Alberta who visited a Mint Pharmacy will receive one of two types of letters: one highlighting flu and heart health benefits, …

This study tests whether a special diet called the MIND diet can help prevent memory loss and dementia in people who have had a stroke. Researchers will compare the MIND diet to usual post-stroke care in 250 adults aged 55 and older. The goal is to see if the diet protects the br…

This study tests whether a safe, non-invasive brain stimulation technique called tDCS can be used at home to boost recovery of memory, language, and thinking skills in people with stroke, brain tumors, or neurodegenerative conditions like Parkinson's or Alzheimer's. Participants …

This study tests a device that combines a motorized knee brace with muscle stimulation to help people who have had a stroke walk more easily and safely. Five veterans with leg weakness or stiffness after stroke will try the device during walking and stair climbing. The goal is to…

This study tests whether adding an interactive screen (MYRO) to standard therapy helps people who had a stroke and struggle with neglect—a condition where they ignore one side of space. About 30 adults with left-sided neglect after a recent stroke will be split into two groups: o…

This study tests a motorized walking trainer that gives gentle assistance and sound cues to help stroke survivors with leg weakness walk more naturally. The goal is to see if it improves walking symmetry, hip movement, and speed. The study will include 60 adults who have had a st…

This study tests whether acceptance and commitment therapy (ACT), delivered online in groups, can help stroke survivors adjust to life after their stroke. Five adults who had a stroke at least three months ago will attend weekly video sessions for eight weeks and complete questio…

This study tests a simple idea: temporarily numbing non-paralyzed arm muscles with over-the-counter cream while exercising paralyzed muscles. Researchers want to see if this helps improve strength, function, and sensation in people with spinal cord injury. About 30 adults with in…

This study tested whether combining gentle touch stimulation with nerve mobilization exercises could improve arm movement and sensation in people who had a stroke 6 to 12 months earlier. 53 participants with lasting arm weakness and numbness were enrolled. The goal was to see if …

This pilot study explores whether fine motor hand exercises can improve swallowing skills in older adults who recently had a stroke. About 30 participants over age 70 with swallowing problems will be enrolled. The goal is to see if activating hand and mouth brain areas together h…

This study looks at whether gentle electrical stimulation to neck muscles can improve swallowing in people who recently had a stroke. About 40 participants will get either standard swallowing therapy or therapy plus different types of stimulation. The goal is to see if the stimul…

This study looks at whether adding extra sensory feedback to mirror therapy can help stroke survivors regain arm movement. 84 people with arm weakness after a stroke will try one of three types of mirror therapy for 20 sessions. The goal is to see which approach works best for im…

This study looks at whether doing leg exercises with one leg at a time or both legs together, along with visual feedback, helps stroke survivors improve balance, walking, and feeling in their legs. About 50 people who had a stroke more than 3 months ago will take part. They will …

This study tests a nurse-led bedside program to improve trunk control, posture, and breathing in stroke survivors. About 130 stable stroke patients in rehabilitation wards will take part. The program focuses on exercises and care routines to help patients regain core strength and…

This study tests a system called GaitBetter that combines walking and thinking exercises to help people who have had a stroke walk better and avoid falls. About 76 adults aged 18 to 85 who had a stroke (either within the last 8 weeks or more than 6 months ago) and still have trou…

This study tests whether a mild electrical current applied to the scalp, combined with speech therapy, can help people with aphasia (trouble speaking or understanding language) after a stroke. About 200 adults aged 18–85 with language problems from left-brain damage will receive …

This study looks at whether percussion massage therapy (like using a massage gun) can help people who had a stroke more than 6 months ago. The goal is to see if it reduces muscle tightness and improves walking and balance. About 34 adults aged 40-65 with leg weakness after a stro…

This study looks at whether adding foot pressure feedback to robot-assisted walking training helps people who have had a stroke walk more symmetrically and with better balance. About 26 adults with chronic hemiplegia (weakness on one side) will use a Lokomat robot for 30-minute s…

This study tests a new wireless device that uses mild nerve stimulation during physical therapy to help people who had a stroke at least a year ago. The goal is to see if it is safe and can improve arm and hand movement. About 42 adults aged 22 to 79 with moderate arm weakness wi…

This study tests whether pairing a gentle brain-stimulation technique (transcranial direct current stimulation) with core stability exercises can improve trunk performance, balance, and daily mobility in people who have had a stroke. The trial will enroll 60 adults aged 55 or old…

This study tests a 12-session telehealth program called teleABLE that helps stroke survivors reduce sitting time and improve quality of life. 90 adults who had a stroke within the past year will either get teleABLE or a health education program. Participants wear an activity moni…

This study tests whether a small vibrating device worn on the wrist can improve hand movement and feeling in people who had a stroke at least six months ago. The device uses gentle vibrations to boost touch sensation, which may help with grip and dexterity. The main goal is to se…

This study tests a new therapy for stroke survivors who have spatial neglect, a condition where they ignore one side of their world. The therapy uses moving sounds to gently guide their attention to the neglected side. Eighteen adults with stroke will either get standard rehab or…

This study tests whether adding a gentle electrical current to leg muscles during exercise can improve foot movement and reduce stiffness in people who had a stroke at least 6 months ago. 25 adults aged 43-83 with mild foot weakness will be split into two groups: one gets standar…

This study tested whether a device that reads muscle signals can help stroke survivors with severe arm weakness improve their movement during early rehabilitation. Three veterans who had a stroke within the past 6 months used the device alongside standard care. The goal was to se…

This study tests whether the Ronnie Gardiner Method, a structured music and rhythm training program, can improve balance and other functions in people who had a stroke more than six months ago. Eighty adults will be randomly assigned to either 12 weeks of twice-weekly RGM trainin…

This study tests a new walking trainer for people recovering from a stroke. The device supports the waist and uses sound cues to help patients walk more naturally on the ground. Researchers will measure improvements in walking speed, step length, and pelvic rotation in 40 adult s…

This study looks at whether using a robotic exoskeleton for arm exercises helps people who had a stroke regain arm function better than traditional rehab. It includes 70 adults who had a first stroke within the last 90 days and have moderate to severe arm weakness. Participants w…

This study tests whether vibrating the tendons, combined with robotic arm training, can improve arm and hand function in people who had a stroke at least 6 months ago. 40 participants will receive the therapy, and researchers will measure changes in movement and sensation. The go…

This study is testing a set of virtual reality games (exergames) in the Metaverse to help people with neurological conditions like multiple sclerosis, Parkinson's disease, stroke, and traumatic brain injury improve their cognitive skills. The games include cooking together, solvi…

This study compares two approaches to help stroke survivors with mild-to-moderate thinking problems. Both use a computer game to train how quickly the brain processes information. One group also practices everyday tasks and learns ways to use these skills at home, while the other…

This study tests a program that helps family caregivers of stroke survivors learn skills to manage care and reduce stress. About 332 caregivers will receive nine nurse-led phone calls over several months. The goal is to improve caregivers' well-being and reduce depression.

This study is testing whether adding abdominal electrical stimulation to standard core exercises helps stroke patients improve their balance and trunk muscle strength. A small group of stroke survivors will either do exercises alone or exercises plus the stimulation. Researchers …

This study is testing an 8-week online program designed to help couples where one person has had a stroke. The program teaches skills like communication, gratitude, and goal-setting to reduce anxiety and depression in both the stroke survivor and their partner. Researchers aim to…

This study looks at whether a specific brain marker can help predict how well stroke survivors recover from spatial neglect—a condition that affects awareness of space and makes daily tasks difficult. Researchers will follow 45 Veterans for six months, measuring their functional …

This study collects movement data from 250 people with stroke, Parkinson's, or leg amputations using wearable sensors and video. The goal is to create a database that researchers can use to better understand movement and rehabilitation. Participants range from newborns to 99 year…

This study follows about 3,000 adults in Port-au-Prince, Haiti, for up to 7 years to track heart disease risks like high blood pressure, diabetes, and smoking. Researchers will measure how common these risks are and how they lead to heart attacks, strokes, or heart failure. The g…

This study looks at whether shoulder problems can affect balance in people who have had a stroke and have weakness on one side (hemiplegia). Researchers will compare two groups of 100 stroke survivors — those with shoulder pain and those without — using pain scales and balance te…

This study follows over 19,000 older adults who previously took aspirin in a clinical trial. Researchers are monitoring for long-term effects, especially on cancer, dementia, and disability. No new treatment is given—participants just continue regular check-ups and phone calls to…

This study reviews over 2,500 medical records to understand why some people with treated and controlled high blood pressure still die from heart attacks, strokes, kidney failure, or sudden death. It aims to find overlooked factors beyond blood pressure numbers that may lead to fa…

This study aims to see if a handheld tool can accurately measure spasticity (muscle stiffness) in people who have had a stroke. Researchers will compare the device's readings to standard clinical tests. The study involves 40 adults aged 18-75 with a history of stroke on one side …

This study watches 1,000 stroke patients over time to learn how the brain heals. Researchers use brain scans, electrical signals, and movement tests to find patterns. No new treatments are tested—the goal is to better predict recovery and understand stroke's effects.

This study measures how much force leg muscles can produce and how they use oxygen in people who have had a stroke or have sarcopenia (age-related muscle loss). Researchers will test hip, knee, and ankle strength at different angles and speeds. The goal is to use this data to des…

This study explores whether combining physical and mental tasks (like walking while solving a puzzle) can improve rehabilitation for people with stroke, multiple sclerosis, Parkinson's disease, or long COVID. Researchers will test these strategies in small groups to see if they a…

This study looks at how quickly stroke survivors can process information and whether that speed affects their movement, balance, walking, and quality of life. Researchers will test 100 people who had a single ischemic stroke. The goal is to understand the link between thinking sp…

This study aimed to test whether a virtual reality (VR) system focused on everyday tasks could help people with acquired brain injury improve arm movement and quality of life. It planned to include adults at least two months post-stroke with some arm impairment. However, the stud…

This study works with stroke survivors, their carers, and healthcare staff to create a program that helps people stay physically active after finishing rehab. Many stroke survivors struggle to keep exercising on their own, which raises their risk of another stroke. The goal is to…

This study follows 102 adults with sickle cell disease to understand how often silent and overt strokes occur. Researchers use MRI scans and neurological exams to track strokes over time. The goal is to gather the data needed to design future clinical trials for stroke prevention…

This study looks at how people who have had a stroke use healthcare services over the long term. Researchers will review medical records of about 40,000 patients and interview 240 stroke survivors to understand their needs and experiences. The goal is to find ways to improve heal…

This study looks at whether a mobile rehab app, paired with a community health worker visiting at home, can help stroke survivors in the Rio Grande Valley recover better. Eleven uninsured adults who had a first stroke within the past 3 months are taking part. Researchers will mea…

This study looks at whether a new way of analyzing brain scans can better predict stroke risk in people with narrowed arteries in the brain. Researchers will use a special computer method to measure blood flow from routine angiograms. 400 adults with moderate to severe narrowing …

This study looks at whether a new, organized way of routing stroke patients to hospitals can help more people with severe strokes get a life-saving clot-removal procedure. About 4,900 adults in Alabama with suspected severe stroke will be included. The approach uses a central com…

This study follows 600 people with and without chronic kidney disease (CKD) for up to 4 years to see how memory, thinking, and daily activities change over time. Researchers will compare the two groups and look for risk factors that may lead to cognitive decline, dementia, or str…

This study tests whether a travel-themed board game called 'LOHAS Journey' can help older adults (ages 65-100) who have had a mild to moderate stroke think about and express their preferences for life-sustaining treatments. The game uses blocks and cards to make advance care plan…

This study explores whether a virtual reality system called AdaptRehab imVR can help people in Ethiopia recover arm movement after a stroke. Researchers will test the system with 18 adults who had a stroke within the last six months or more. The goal is to see if the VR approach …

This study looks at why some people with a stroke get to the hospital later than others. Researchers will use a questionnaire, mapping tools, and brain scans to find non-medical barriers like transportation or lack of knowledge. They aim to build a machine learning model that pre…

This study watches people with brain conditions like traumatic brain injury, cerebral palsy, or Alzheimer's who choose to get special nasal treatments with stem cells or exosomes. Researchers do not give the treatment but collect safety data and measure inflammation markers in th…

This study looks at how a soft robotic exosuit can help people who had a stroke more than six months ago walk better. Researchers will measure muscle activity and walking patterns with and without the suit to see who benefits most. The goal is to understand how the brain controls…

This study follows 1,000 people with atrial tachycardia to see how well different treatments work over time. Researchers track serious outcomes like death, stroke, and hospital stays. The goal is to learn which approaches are safest and most effective for long-term care.

This study tests whether combining in-person therapy with video calls and apps works as well as traditional all-in-person rehab for people recovering from stroke, brain bleeding, or head injury. About 30 adults will try both approaches in a different order to see which is more ef…

This study looks at brain activity and heart rhythms in 45 people—some who have had a stroke and some who are healthy. Researchers use special head sensors (fNIRS and EEG) and heart monitors (ECG) to measure differences while participants rest with their eyes closed. The goal is …

This study looks at 602 people who had a stroke to see how often seizures occur afterward. Researchers check brain wave patterns (EEG), blood tests, and brain scans to find clues that might predict seizures. The goal is to better understand who is at risk, not to test a new treat…

This study watches 200,000 Chinese adults with heart disease over five years. Researchers use exercise tests to measure heart and lung fitness and see if those results can predict future heart problems like heart attacks or hospital stays. No new treatments are tested—the goal is…

This study gathers information from 8,000 people who had a stroke and later developed seizures or epilepsy. Researchers will analyze this data to understand how these patients recover and to create a tool that predicts who might develop epilepsy after a stroke. The goal is to imp…

This study looks at whether stroke patients who do high-intensity rehabilitation at home recover their physical function as well as those who go to an inpatient rehab facility. Researchers will track 500 patients from Duke University Hospital, comparing outcomes like mobility and…

This study tests a new therapy program called REAP for stroke survivors in Bangladesh. The program helps people regain skills, learn about stroke, adapt their daily tasks, and get back to meaningful activities. Six participants will try the program to see if it works and is accep…

This study aims to make it easier and more accurate to detect tiny blood clots in the brain using ultrasound. These clots, called microemboli, can predict future strokes. Researchers will have multiple experts review recordings to create a standard way to identify them, which cou…

This study looks at how common strokes and silent brain injuries are in young adults (ages 16-25) with sickle cell anemia in northern Nigeria. Researchers will use brain scans and blood flow tests to find hidden damage and check for risk factors like high blood pressure. The goal…

This study is testing a program called CONNECT that helps more women and Black and Latino adults learn about and join heart health research. About 1,000 people with heart disease or risk factors like high blood pressure or diabetes will receive text messages with heart health inf…

This study looks at whether a specific breathing method, called acute intermittent hypoxia (brief periods of low oxygen), can improve arm function in people who had a stroke at least 6 months ago. Researchers will measure arm strength and reflexes in 20 participants to understand…

This study looks at how simple balance tests can help doctors tell the difference between various causes of balance problems, such as stroke, inner ear issues, vision problems, or spine conditions. Researchers will test 330 people, including healthy volunteers and patients with d…

This study planned to see if a soft robotic exosuit could help people who had a stroke walk better by combining high-intensity training with good movement quality. The researchers wanted to enroll adults aged 18-80 who had a stroke at least 6 months ago and had trouble walking. H…

This study looks back at the medical records of 2,500 people who had thinking and memory tests before and after hyperbaric oxygen therapy (HBOT). The goal is to see if HBOT is linked to improvements in cognitive function for patients with traumatic brain injury, stroke, fibromyal…

This study tests whether personalized educational videos can improve stroke survivors' understanding of their condition and risk factors. About 100 people who had a stroke 1-10 years ago will use a custom app and answer surveys after 7 and 90 days. The goal is to see if this appr…

This study explores a new program that supports physical activity in the first 6 weeks after a stroke. About 25 participants will use a Fitbit to track steps and meet weekly with an occupational therapist. The goal is to see if people stick with the program and find it helpful, n…

This study looks at 10,000 people who have both sleep apnea and high blood pressure. Researchers will track them over many years to see how well they use their sleep apnea machine (PAP) and blood pressure medicines, and whether that affects their risk of heart attacks, strokes, h…

This study is creating a large biobank of health information and blood samples from 48,000 people with diabetes in Hong Kong. Researchers will analyze genes and other markers to better predict who is at risk for serious complications like kidney failure, heart disease, and stroke…

This study examines whether a common gene variation (CYP2C19) affects the long-term risk of serious heart and blood vessel problems, such as heart attacks, strokes, and limb complications. Researchers will analyze medical records from 13,000 adults who have already had genetic te…

This study was designed to see if a cholesterol-lowering drug called a PCSK9 inhibitor could also reduce inflammation in the arteries of people with heart disease. Researchers planned to use a special imaging scan to measure inflammation. However, the study was withdrawn before e…

This study tests whether watching storytelling videos can help African American and Black patients with atrial fibrillation (an irregular heartbeat) start and continue taking blood thinners to prevent strokes. About 80 adults who are not currently on blood thinners but should be …

This study looks at how stroke changes the way people feel touch when they move their muscles. Researchers will test 45 stroke survivors and compare their ability to detect mild electrical pulses on the skin at rest and during muscle activation. The goal is to better understand t…

This study follows 1,000 stroke survivors and their caregivers over time to understand what matters most to them after a stroke. Researchers will use surveys to track recovery and see how social factors like income, housing, and experiences of discrimination affect long-term outc…

This study tests a new way to grade carotid plaques using ultrasound, called Plaque-RADS, to see if it can predict stroke risk better than current methods. Researchers will collect data from 855 people with asymptomatic carotid plaques and build a risk model. The goal is to ident…

This study looks at balance and walking problems in people with stroke, Parkinson's disease, or multiple sclerosis. Researchers will use special devices to measure how stable patients are and how they walk. The goal is to better understand these issues so that rehabilitation can …

This study follows 300 children who had seizures as newborns to understand how genes influence their risk of developing epilepsy later in childhood. Researchers will combine genetic, brain scan, and EEG data to create a risk score. The goal is to better predict which children nee…

This study aimed to see if stroke patients could use an augmented reality (AR) program for arm rehabilitation at home. Researchers planned to track how often patients completed their sessions and whether they could perform an AR-based assessment. However, the study was withdrawn …

This study looks at how a gentle ultrasound pulse to the cerebellum (the part of the brain that controls coordination and some thinking) changes brain waves and mental tasks. Twenty healthy adults aged 18 to 40 will receive both real and fake (sham) ultrasound while their brain a…

This study looks at how nerve reflexes in the thigh muscle affect walking in people who have had a stroke and have a stiff-knee gait. Researchers use mild electrical stimulation to measure reflex activity while participants walk. The goal is to better understand the link between …

This study follows over 2,400 people who had their first stroke to track their recovery over 10 years. Researchers measure daily living skills, mood, and quality of life to find what helps or hinders long-term improvement. The goal is to better understand stroke recovery and impr…

This study aims to create a toolkit that helps stroke survivors and hospital staff stick to the rules of rehabilitation trials. Researchers will work with stroke survivors, their families, therapists, and healthcare leaders to identify common problems and design practical solutio…

This study looks at whether a computer-guided breathing machine (ventilator) protocol can help patients with serious brain injuries. The goal is to use low air volumes to protect the lungs while keeping carbon dioxide levels normal for the brain. About 728 adults on ventilators w…

This long-term study aims to understand how early, hidden signs of heart disease develop and predict future heart attacks, strokes, and heart failure. It follows over 6,400 adults from four different ethnic groups who started the study with no known heart disease. Researchers use…