New balloon coated with paclitaxel aims to keep brain arteries open
NCT ID NCT06047964
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a special balloon catheter coated with the drug paclitaxel to treat narrowed or re-narrowed brain arteries. The balloon is inflated inside the artery to open it and release the drug, which may help prevent the artery from closing again. The trial includes 281 adults aged 18 to 80 with symptomatic intracranial atherosclerosis or restenosis after prior treatment. Researchers will measure how often the artery narrows again and track patients' disability levels over 12 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
paclitaxel-coated balloon catheter
What this could lead to
If successful, this could offer a new way to reopen narrowed brain arteries and reduce the risk of stroke in patients with intracranial atherosclerosis.
What could go wrong
This is an early-stage device trial without a randomized control group, so results may not confirm superiority over standard balloons. Risks include vessel injury or restenosis despite treatment.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for STROKE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
First Hospital of Shanxi Medical University
Taiyuan, Shanxi, China
-
Jining First People's Hospital
Jining, Shandong, China
-
Nanyang Central Hospital
Nanyang, Henan, China
-
Renji Hospital, Shanghai Jiaotong University, School of Medicine
Shanghai, Shanghai Municipality, China
-
The Affiliated Hospital of Qingdao University
Qingdao, Shandong, China
-
The First Affiliated Hospital of Harbin Medical University
Harbin, Heilongjiang, China
-
The First Hospital of Jilin University
Changchun, Jilin, China
-
The Second Affiliated Hospital Zhejiang University School of Medicine
Hangzhou, Zhejiang, China
-
Xuanwu Hospital, Capital Medical University
Beijing, Beijing Municipality, 100000, China