Aspirin's hidden legacy: 19,000 seniors tracked for delayed effects

NCT ID NCT07224347

Ongoing Knowledge-focused Sponsor: Anne Murray Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows over 19,000 older adults who previously took aspirin in a clinical trial. Researchers are monitoring them for delayed effects on cancer, dementia, disability, and death. The goal is to see if aspirin has any long-term benefits or risks years after stopping the medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could clarify whether taking aspirin has long-term benefits or risks for older adults, especially regarding cancer and dementia.
What could go wrong: This is an observational follow-up, not a new treatment trial. Results may show no clear effects or be limited by the original study's design and participant health.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer dementia Depression depressive disorder Frailty heart disorder Hemorrhage hemorrhagic disease neoplasm stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BLEEDING CANCER DEMENTIA DEPRESSION FRAILTY FUNCTIONAL DISABILITY HEART DISEASE STROKE

Contacts and locations

Locations

Bendigo Regional Clinical School

Bendigo, Victoria, 3550, Australia
Clinical Trials Unit, The Canberra Hospital

Garran, Australian Capital Territory, 2605, Australia
Discipline of General Practice, School of Population Health, University of Adelaide

Adelaide, South Australia, 5005, Australia
Einstein Medical Center

Philadelphia, Pennsylvania, 19141, United States
Emory/ Atlanta VAMC

Atlanta, Georgia, 30322, United States
Gateway Community Health

Wodonga, Victoria, 3690, Australia
Geelong Hospital

Geelong, Victoria, 3220, Australia
Greater Green Triangle University

Mount Gambier, South Australia, 5290, Australia
HealthPartners Research Institute

Minneapolis, Minnesota, 55425, United States
Howard University

Washington D.C., District of Columbia, 20060, United States
Illawarra Health and Medical Research Institute, University of Wollongong

Wollongong, New South Wales, 2522, Australia
Kent County Memorial Hospital

Pawtucket, Rhode Island, 02860, United States
LSU Health Sciences- Shreveport

Shreveport, Louisiana, 71130, United States
Monash Gippsland Regional Clinical School

Traralgon, Victoria, 3844, Australia
Monash Mildura Regional Clinical School

Mildura, Victoria, 3500, Australia
Morehouse School of Medicine

Atlanta, Georgia, 30310, United States
Pennington Biomedical Research Center

Baton Rouge, Louisiana, 70808, United States
Phalen Village Clinic

Saint Paul, Minnesota, 55106, United States
Regional Academic Health Center

Harlingen, Texas, 78550, United States
Rush Alzheimer's Disease Center

Chicago, Illinois, 60612, United States
The Brody School of Medicine at East Carolina University

Greenville, North Carolina, 27834, United States
The Menzies Institute for Medical Research, University of Tasmania

Hobart, Tasmania, 7000, Australia
The South West Alliance of Rural Health (SWARH)

Warrnambool, Victoria, 3280, Australia
The University of Alabama at Birmingham

Birmingham, Alabama, 35294, United States
UT Health Science Center at San Antonio

San Antonio, Texas, 78229, United States
University of Ballarat

Mount Helen, Victoria, 3350, Australia
University of Iowa

Iowa City, Iowa, 52242, United States
University of Michigan

Ann Arbor, Michigan, 48109, United States
University of Pittsburgh Health Sciences Research Center

Pittsburgh, Pennsylvania, 15260, United States
University of Tasmania Newnham Campus

Launceston, Tasmania, 7250, Australia
University of Tasmania Rural Clinical School

Burnie, Tasmania, 7320, Australia
University of Tennessee Health Science Center

Memphis, Tennessee, 38105, United States
University of Texas Medical Branch

Galveston, Texas, 77555, United States
University of Texas Southwestern Medical Center at Dallas

Dallas, Texas, 75390, United States
Wake Forest University Baptist Medical Center

Greensboro, North Carolina, 27408, United States
Wayne State University

Detroit, Michigan, 48201, United States

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